murder

affliction, calvary, cross, curse, ordeal, trial, tribulation

calamity, misfortune, tragedy

gall, thorn

bummer, downer, drag

chance-medley, killing, manslaughter

bloodshed, butchery, carnage, decimation, destruction, massacre, slaughter

assassination, execution, hit

euthanasia, mercy killing

filicide, fratricide, matricide, parricide, patricide, regicide, uxoricide

blow away, shoot, shoot down

blot out, carry off, claim, cut down, destroy, fell, kill, smite, zap

butcher, massacre, mow (down), slaughter

annihilate, eliminate, eradicate, exterminate, wipe out

blunder, gum (up), muddle, piffle

blemish, blight, damage, flaw, harm, hurt, impair, injure, mar, mutilate, ruin, spoil, vitiate

destroy, wreck

mishandle, mismanage