Synonyms of misfortune

misfortune

noun

ˌmis-ˈfȯr-chən 

as in tragedy

bad luck or an example of this

through sheer misfortune our car got a flat tire and we were late for the ceremony

our misfortunes of the last year included the loss of a beloved pet

Synonyms & Similar Words

• tragedy
• hardship
• misery
• mishap
• disaster
• ill
• trouble
• adversity
• accident
• mischance
• misadventure
• catastrophe
• fate
• calamity
• trial
• suffering
• circumstance
• sorrow
• knock
• disappointment
• doom
• defeat
• blow
• curse
• woe
• distress
• unhappiness
• failure
• evil
• tribulation
• setback
• destiny
• casualty
• affliction
• cataclysm
• portion
• letdown
• nonsuccess
• fizzle
• body blow
• lot

Antonyms & Near Antonyms

• luck
• fortune
• opportunity
• chance
• stroke
• success
• strike
• hit
• serendipity
• break
• windfall
• achievement
• fluke
• accomplishment
• godsend

Synonym Chooser

How does the noun misfortune differ from other similar words?

Some common synonyms of misfortune are adversity, mischance, and mishap. While all these words mean "adverse fortune or an instance of this," misfortune may apply to either the incident or conjunction of events that is the cause of an unhappy change of fortune or to the ensuing state of distress.

never lost hope even in the depths of misfortune

When might adversity be a better fit than misfortune?

The words adversity and misfortune are synonyms, but do differ in nuance. Specifically, adversity applies to a state of grave or persistent misfortune.

had never experienced great adversity

When could mischance be used to replace misfortune?

Although the words mischance and misfortune have much in common, mischance applies especially to a situation involving no more than slight inconvenience or minor annoyance.

took the wrong road by mischance

When can mishap be used instead of misfortune?

While the synonyms mishap and misfortune are close in meaning, mishap applies to an often trivial instance of bad luck.

the usual mishaps of a family vacation

Example Sentences

Recent Examples of misfortune

Even as Chisholm spent several minutes on the ground writhing in pain, a few of his teammates, including Judge, Grisham and Clarke Schmidt, couldn’t help but smirk at his misfortune. — Gary Phillips, New York Daily News, 19 June 2026

Repairing Furniture There are few misfortunes greater than scratching a new piece of dark wood furniture. — Joey Skladany, Southern Living, 17 June 2026

Between 2020 and 2023, I was blessed with two trips to Prentice Women’s Hospital for the birth of my two children and had the misfortune of making several urgent trips to Lurie’s Children’s Hospital. — Chicago Tribune, 12 June 2026

So when the dog is lost in a severe storm that devastates the region and leaves many homeless, an overwhelmed Rose must balance the urgency of her search mission alongside the misfortune of others close to her. — Guy Lodge, Variety, 8 June 2026