disease

noun

dis·​ease di-ˈzēz How to pronounce disease (audio)
1
: a condition of the living animal or plant body or of one of its parts that impairs normal functioning and is typically manifested by distinguishing signs and symptoms : sickness, malady
infectious diseases
a rare genetic disease
heart disease
2
: a harmful development (as in a social institution)
sees the city's crime as a disease
3
obsolete : trouble

Examples of disease in a Sentence

He suffers from a rare genetic disease. a disease of the mind Thousands die of heart disease each year. They are working to stop the spread of disease in rural areas. The article cites intolerance as one of the most dangerous of society's diseases. He sees crime as a disease that too often plagues the poor and disadvantaged.
Recent Examples on the Web
Examples are automatically compiled from online sources to show current usage. Read More Opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback.
Besides being nuisances, many types carry diseases including West Nile virus, encephalitis, and canine heartworm. Arricca Elin Sansone, Southern Living, 11 May 2025 An Ohio music conductor is using deep brain stimulation to combat his Parkinson’s disease. Khloe Quill, FOXNews.com, 10 May 2025 However, in the 1950s, Panama disease — caused by Fusarium oxysporum f. sp. cubense Tropical Race 1 — began ravaging across Gros Michel farms in Costa Rica, Panama and beyond. Scott Travers, Forbes.com, 10 May 2025 Minnesota newborns will soon be screened for a disease that can lead to delays in developmental milestones, regression of skills, seizures and in some cases death. Kristi Miller, Twin Cities, 10 May 2025 See All Example Sentences for disease

Word History

Etymology

Middle English disese, from Anglo-French desease, desaise, from des- dis- + eise ease

First Known Use

14th century, in the meaning defined at sense 3

Time Traveler
The first known use of disease was in the 14th century

Browse Nearby Words

Cite this Entry

“Disease.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/disease. Accessed 18 May. 2025.

Kids Definition

disease

noun
dis·​ease diz-ˈēz How to pronounce disease (audio)
: an abnormal bodily condition of a living plant or animal that interferes with functioning and can usually be recognized by signs and symptoms : illness
diseased adjective

Medical Definition

disease

noun
dis·​ease diz-ˈēz How to pronounce disease (audio)
: an impairment of the normal state of the living animal or plant body or one of its parts that interrupts or modifies the performance of the vital functions, is typically manifested by distinguishing signs and symptoms, and is a response to environmental factors (as malnutrition, industrial hazards, or climate), to specific infective agents (as worms, bacteria, or viruses), to inherent defects of the organism (as genetic anomalies), or to combinations of these factors : sickness, illness

called also morbus

compare health sense 1
diseased adjective

More from Merriam-Webster on disease

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