Paget's disease

noun
Pag·​et's disease | \ˈpa-jəts- \

Definition of Paget's disease 

1 : a rare form of breast cancer initially manifested as a scaly red rash on the nipple and areola

2 or Paget's disease of bone : a chronic disease that is characterized by one or more enlarged, weak bones (such as of the pelvis, spine, or skull) and may be marked by bone pain but is often asymptomatic

Note: Paget's disease is caused by a high level of bone resorption by osteoclasts followed by rapid formation of structurally unsound bone by osteoblasts. Symptoms include bowing of the long bones, deformation of the skull and pelvis, and abnormal fractures occurring in weakened bone.

First Known Use of Paget's disease

1880, in the meaning defined at sense 1

History and Etymology for Paget's disease

Sir James Paget †1899 English surgeon

Keep scrolling for more

Learn More about Paget's disease

Share Paget's disease

Dictionary Entries near Paget's disease

page proof

pager

Paget

Paget's disease

page through

Paget process

page-turner

Statistics for Paget's disease

Look-up Popularity

Time Traveler for Paget's disease

The first known use of Paget's disease was in 1880

See more words from the same year

Keep scrolling for more

More Definitions for Paget's disease

Paget's disease

noun
Pag·​et's disease | \ˌpaj-əts- \

Medical Definition of Paget's disease 

1 : a rare form of breast cancer initially manifested as a scaly red rash on the nipple and areola

2 or Paget's disease of bone : a chronic disease that is characterized by one or more enlarged, weak bones (such as of the pelvis, spine, or skull) and may be marked by bone pain but is often asymptomatic

Note: Paget's disease is caused by a high level of bone resorption by osteoclasts followed by rapid formation of structurally unsound bone by osteoblasts. Bowing of the long bones, deformation of the flat bones, and abnormal fractures occur in the weakened bone.

called also osteitis deformans, osteodystrophia deformans

Comments on Paget's disease

What made you want to look up Paget's disease? Please tell us where you read or heard it (including the quote, if possible).

WORD OF THE DAY

the figure or shape of a crescent moon

Get Word of the Day daily email!

Test Your Vocabulary

Late Autumn 2018 Words of the Day Quiz

  • frosted-autumn-leaves
  • Which is a synonym of yahoo?
True or False

Test your knowledge - and maybe learn something along the way.

TAKE THE QUIZ
SCRABBLE® Sprint

Test Your Knowledge - and learn some interesting things along the way.

TAKE THE QUIZ

Love words? Need even more definitions?

Subscribe to America's largest dictionary and get thousands more definitions and advanced search—ad free!