complication

noun

com·​pli·​ca·​tion ˌkäm-plə-ˈkā-shən 

1

a

: complexity, intricacy

especially : a situation or a detail of character complicating the main thread of a plot

b

: a making difficult, involved, or intricate

c

: a complex or intricate feature or element

d

: a difficult factor or issue often appearing unexpectedly and changing existing plans, methods, or attitudes

2

: a secondary disease or condition developing in the course of a primary disease or condition

Synonyms of complication

• difficulty
• complexity

Examples of complication in a Sentence

The negotiations stalled when complications arose.

Pneumonia is a common complication of AIDS.

She experienced complications during her pregnancy.

The patient died of complications from surgery.

Recent Examples on the Web

Hyper-specialized cardiac surgeons, for example, have fewer complications than their less-specialized peers. —Rachel Barr, Big Think, 29 Jan. 2026

In some cases, COVID-19 can lead to pneumonia or cause complications involving the heart, blood vessels or other organs, according to the CDC. —Sacbee.com, 29 Jan. 2026

The pair did well in Orlando, but there were complications, Ricci said. —David Goodhue, Miami Herald, 29 Jan. 2026

After years of struggles with hearing loss, Bonnie Covey's personal story of restoration has helped others with their complications. —Ray Padilla, Louisville Courier Journal, 29 Jan. 2026

Word History

Etymology

Middle English complicacioun, borrowed from Late Latin complicātiōn-, complicātiō "folding together, conglomeration," from Latin complicāre "to fold together, fold up" + -tiōn-, -tiō, suffix of verbal action — more at complicate entry 2

First Known Use

15th century, in the meaning defined at sense 1a

Rhymes for complication

• abdication
• aberration
• abjuration
• abnegation
• abrogation
• acceptation
• acclamation
• acclimation
• accusation
• activation
• actuation
• acylation

Kids Definition

complication

noun

com·​pli·​ca·​tion ˌkäm-plə-ˈkā-shən 

1

a

: an act or instance of complicating something

b

: a situation or detail of character that complicates a plot

c

: a complex feature or element

d

: something that makes a situation more complicated or difficult

we were unable to agree when complications arose

2

: a disease or bodily condition existing at the same time as and affecting the course or severity of another disease or condition

Medical Definition

complication

noun

com·​pli·​ca·​tion ˌkäm-plə-ˈkā-shən 

: a secondary disease or condition that develops in the course of a primary disease or condition and arises either as a result of it or from independent causes