complication

noun

com·​pli·​ca·​tion ˌkäm-plə-ˈkā-shən 

1

a

: complexity, intricacy

especially : a situation or a detail of character complicating the main thread of a plot

b

: a making difficult, involved, or intricate

c

: a complex or intricate feature or element

d

: a difficult factor or issue often appearing unexpectedly and changing existing plans, methods, or attitudes

2

: a secondary disease or condition developing in the course of a primary disease or condition

Synonyms

• complexity
• complicacy
• convolution
• difficulty
• intricacy

Examples of complication in a Sentence

The negotiations stalled when complications arose.

Pneumonia is a common complication of AIDS.

She experienced complications during her pregnancy.

The patient died of complications from surgery.

Recent Examples on the Web

Things have reportedly gotten so bad that when Charles was hospitalized on March 27 related to complications from his treatment, Harry learned about it through the media. —Stephanie Nolasco, FOXNews.com, 17 Apr. 2025

According to People, a spokesperson from the Chief Medical Examiner’s Office confirmed on Wednesday (April 16) that the actress’s passing was ruled as natural, resulting from complications of diabetes mellitus. —Tyler Jenke, Billboard, 17 Apr. 2025

Nearly 1 to 3 of every 1,000 children who become infected with measles will die from respiratory and neurologic complications. —Matt Leclercq, Fort Worth Star-Telegram, 15 Apr. 2025

The vaccine can reduce a person’s risk of getting whooping cough or having severe complications if they do get infected, according to the Cleveland Clinic. —Chantelle Lee, Time, 15 Apr. 2025

Word History

Etymology

Middle English complicacioun, borrowed from Late Latin complicātiōn-, complicātiō "folding together, conglomeration," from Latin complicāre "to fold together, fold up" + -tiōn-, -tiō, suffix of verbal action — more at complicate entry 2

First Known Use

15th century, in the meaning defined at sense 1a

Rhymes for complication

• abdication
• aberration
• abjuration
• abnegation
• abrogation
• acceptation
• acclamation
• acclimation
• accusation
• activation
• actuation
• acylation

Kids Definition

complication

noun

com·​pli·​ca·​tion ˌkäm-plə-ˈkā-shən 

1

a

: an act or instance of complicating something

b

: a situation or detail of character that complicates a plot

c

: a complex feature or element

d

: something that makes a situation more complicated or difficult

we were unable to agree when complications arose

2

: a disease or bodily condition existing at the same time as and affecting the course or severity of another disease or condition

Medical Definition

complication

noun

com·​pli·​ca·​tion ˌkäm-plə-ˈkā-shən 

: a secondary disease or condition that develops in the course of a primary disease or condition and arises either as a result of it or from independent causes