Tay-Sachs disease

noun
\ ˈtā-ˈsaks- How to pronounce Tay-Sachs disease (audio) \

Definition of Tay-Sachs disease

: a hereditary disorder of lipid metabolism typically affecting individuals of eastern European Jewish ancestry that is characterized by the accumulation of lipids especially in nervous tissue due to a deficiency of hexosaminidase, that is inherited as a recessive autosomal trait, and that causes death in early childhood

called also Tay-Sachs

First Known Use of Tay-Sachs disease

1907, in the meaning defined above

History and Etymology for Tay-Sachs disease

Warren Tay †1927 British physician & Bernard P. Sachs †1944 American neurologist

Keep scrolling for more

Learn More about Tay-Sachs disease

Time Traveler for Tay-Sachs disease

Time Traveler

The first known use of Tay-Sachs disease was in 1907

See more words from the same year

Statistics for Tay-Sachs disease

Cite this Entry

“Tay-Sachs disease.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/Tay-Sachs%20disease. Accessed 24 May. 2020.

Keep scrolling for more

More Definitions for Tay-Sachs disease

Tay-Sachs disease

noun
\ ˈtā-ˈsaks- How to pronounce Tay-Sachs disease (audio) \

Medical Definition of Tay-Sachs disease

: a hereditary disorder of lipid metabolism that typically affects individuals of eastern European Jewish ancestry, that is marked by the accumulation of lipids especially in nervous tissue due to a deficiency of hexosaminidase A, that is characterized by weakness, macrocephaly, red retinal spots, hyperacusis, retarded development, blindness, convulsions, paralysis, and death in early childhood, and that is inherited as an autosomal recessive trait

called also Tay-Sachs

— see sandhoff's disease

Comments on Tay-Sachs disease

What made you want to look up Tay-Sachs disease? Please tell us where you read or heard it (including the quote, if possible).

WORD OF THE DAY

See Definitions and Examples »

Get Word of the Day daily email!

Test Your Vocabulary

Obscure Shapes

  • a pile of three dimensional shapes in green
  • Something that is ooid is shaped like:
Spell It

Can you spell these 10 commonly misspelled words?

TAKE THE QUIZ
Citation

Test Your Knowledge - and learn some interesting things along the way.

TAKE THE QUIZ
Love words? Need even more definitions?

Subscribe to America's largest dictionary and get thousands more definitions and advanced search—ad free!