Addison's disease


Ad·​di·​son's disease ˈa-də-sənz- How to pronounce Addison's disease (audio)
: a destructive disease marked by deficient adrenocortical secretion and characterized by extreme weakness, loss of weight, low blood pressure, gastrointestinal disturbances, and brownish pigmentation of the skin and mucous membranes

Examples of Addison's disease in a Sentence

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Word History


after Thomas Addison †1860 English physician

First Known Use

circa 1856, in the meaning defined above

Time Traveler
The first known use of Addison's disease was circa 1856

Dictionary Entries Near Addison's disease

Cite this Entry

“Addison's disease.” Dictionary, Merriam-Webster, Accessed 22 May. 2024.

Medical Definition

Addison's disease

: a rare disease marked by deficient secretion of adrenocortical hormones (such as cortisol) that is characterized by fatigue, muscle weakness, weight loss, low blood pressure, irritability or depression, and brownish pigmentation of the skin and is caused by progressive destruction of the adrenal glands (as by an autoimmune response or infection)
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