Addison's disease

Ad·​di·​son's disease | \ ˈa-də-sənz- How to pronounce Addison's disease (audio) \

Definition of Addison's disease

: a destructive disease marked by deficient adrenocortical secretion and characterized by extreme weakness, loss of weight, low blood pressure, gastrointestinal disturbances, and brownish pigmentation of the skin and mucous membranes

First Known Use of Addison's disease

circa 1856, in the meaning defined above

History and Etymology for Addison's disease

after Thomas Addison †1860 English physician

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The first known use of Addison's disease was circa 1856

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Cite this Entry

“Addison's disease.” Dictionary, Merriam-Webster, Accessed 15 Jan. 2021.

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Addison's disease


Medical Definition of Addison's disease

: a rare disease marked by deficient secretion of adrenocortical hormones (such as cortisol) that is characterized by fatigue, muscle weakness, weight loss, low blood pressure, irritability or depression, and brownish pigmentation of the skin and is caused by progressive destruction of the adrenal glands (as by an autoimmune response or infection)

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