Creutzfeldt-Jakob disease


Creutz·​feldt-Ja·​kob disease ˈkrȯits-ˌfelt-ˈyä-(ˌ)kōb- How to pronounce Creutzfeldt-Jakob disease (audio)
variants or less commonly Creutzfeld-Jakob disease
: a rare progressive fatal encephalopathy caused by a prion and marked by development of porous brain tissue, premature dementia in middle age, and gradual loss of muscular coordination

Examples of Creutzfeldt-Jakob disease in a Sentence

Recent Examples on the Web In people, the disease is fatal and called Creutzfeldt-Jakob disease. Susanne Rust, Los Angeles Times, 18 Apr. 2024 Some of the 1,848 patients who received cadaver hormone developed Creutzfeldt-Jakob disease (CJD), a rare but always fatal brain disorder caused by a type of prion known as PrP-amyloid plaques. Erin Prater, Fortune Well, 1 Feb. 2024 The treatment approach was discontinued after cases of a rare brain disorder called Creutzfeldt-Jakob disease were found to be associated with the administration of contaminated human growth hormone from cadavers. Jacqueline Howard, CNN, 29 Jan. 2024 Doctors suspected Mike could have suffered from Creutzfeldt-Jakob disease (CJD), a rare and fatal neurodegenerative disorder in which brain proteins are abnormally folded. Timothy Bella, Washington Post, 9 Nov. 2023 Odd Autopsy Three years ago, Collinge and colleagues found a disturbing collection of clumps in the brains of eight patients who had died of Creutzfeldt-Jakob disease or CJD, a fatal brain disorder. Roni Dengler, Discover Magazine, 13 Dec. 2018 Since his wife Jody died of a rare brain disease (Creutzfeldt-Jakob disease) in 2018, the coach has put even more time into his volunteer work. Ben Thomas |, al, 7 July 2023 Other conditions linked to dementia include Huntington's disease, Parkinson's disease and Creutzfeldt-Jakob disease, which is part of a group of rare fatal brain disorders known as prion diseases. Ken Alltucker, USA TODAY, 30 May 2023 Examples include mad cow disease, scrapie, Kuru, and Creutzfeldt-Jakob disease. William A. Haseltine, Forbes, 9 June 2022

These examples are programmatically compiled from various online sources to illustrate current usage of the word 'Creutzfeldt-Jakob disease.' Any opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback about these examples.

Word History


Hans G. Creutzfeldt †1964 German psychiatrist and Alfons M. Jakob †1931 German psychiatrist

First Known Use

1963, in the meaning defined above

Time Traveler
The first known use of Creutzfeldt-Jakob disease was in 1963

Dictionary Entries Near Creutzfeldt-Jakob disease


Creutzfeldt-Jakob disease


Cite this Entry

“Creutzfeldt-Jakob disease.” Dictionary, Merriam-Webster, Accessed 29 May. 2024.

Medical Definition

Creutzfeldt-Jakob disease

Creutz·​feldt-Ja·​kob disease
variants also Creutzfeld-Jakob disease
: a rare progressive fatal prion disease marked by the development of porous brain tissue, premature dementia in middle age, and gradual loss of muscular coordination
abbreviation CJD

called also Jakob-Creutzfeldt disease

see variant creutzfeldt-jakob disease

More from Merriam-Webster on Creutzfeldt-Jakob disease

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