Creutzfeldt-Jakob disease

noun

Creutz·​feldt-Ja·​kob disease ˈkrȯits-ˌfelt-ˈyä-(ˌ)kōb- 

variants or less commonly Creutzfeld-Jakob disease

: a rare progressive fatal encephalopathy caused by a prion and marked by development of porous brain tissue, premature dementia in middle age, and gradual loss of muscular coordination

Word History

Etymology

Hans G. Creutzfeldt †1964 German psychiatrist and Alfons M. Jakob †1931 German psychiatrist

First Known Use

1963, in the meaning defined above

Medical Definition

Creutzfeldt-Jakob disease

noun

Creutz·​feldt-Ja·​kob disease

variants also Creutzfeld-Jakob disease

ˌkrȯits-ˌfelt-ˌyä-(ˌ)kōb- 

: a rare progressive fatal prion disease marked by the development of porous brain tissue, premature dementia in middle age, and gradual loss of muscular coordination

—abbreviation CJD

called also Jakob-Creutzfeldt disease

see variant creutzfeldt-jakob disease