Creutzfeldt–Jakob disease

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noun Creutz·feldt–Ja·kob disease \ˈkrȯits-ˌfelt-ˈyä-(ˌ)kōb-\

variants: or less commonly

Creutzfeld–Jakob disease

Definition of Creutzfeldt–Jakob disease

: a rare progressive fatal encephalopathy caused by a prion and marked by development of porous brain tissue, premature dementia in middle age, and gradual loss of muscular coordination

See Creutzfeldt–Jakob disease defined for English-language learners

Origin and Etymology of creutzfeldt–jakob disease

Hans G. Creutzfeldt †1964 German psychiatrist and Alfons M. Jakob †1931 German psychiatrist

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First Known Use: 1963

See Words from the same year

CREUTZFELDT–JAKOB DISEASE Defined for English Language Learners

Creutzfeldt-Jakob disease

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noun

Definition of Creutzfeldt–Jakob disease for English Language Learners

medical : a disease of the brain that causes people to lose their memory, to no longer be able to control their muscles, and eventually to die

Medical Dictionary

Creutzfeldt–Jakob disease

noun Creutz·feldt–Ja·kob disease

variants: also

Creutzfeld–Jakob disease

\ˌkrȯits-ˌfelt-ˌyä-(ˌ)kōb-\play

Medical Definition of Creutzfeldt–Jakob disease

: a rare progressive fatal prion disease marked by the development of porous brain tissue, premature dementia in middle age, and gradual loss of muscular coordination—abbreviation CJD; called also Jakob-Creutzfeldt disease; see variant creutzfeldt-jakob disease

Biographical Note for creutzfeldt–jakob disease

Creutzfeldt

\ˈkroits-ˌfelt\,

Hans Gerhard

(1885–1964), and

Jakob

\ˈyä-ˌkōp\,

Alfons Maria

(1884–1931), German psychiatrists. Creutzfeldt published his description of the disease now known as Creutzfeldt-Jakob disease in 1920. A year later in the same neurological journal Jakob offered his description. Although Creutzfeldt's description is the original one, Jakob's is the better known of the two, so the disease is named in honor of both men.