prion disease

:  any of a group of spongiform encephalopathies that are caused and transmitted by prions and that include bovine spongiform encephalopathy, Creutzfeldt-Jakob disease, fatal familial insomnia, Gerstmann-Sträussler-Scheinker syndrome, kuru, scrapie, and variant Creutzfeldt-Jakob disease—called also transmissible spongiform encephalopathy