Lou Gehrig's disease

noun

Lou Geh·​rig's disease ˌlü-ˈger-igz- 

: amyotrophic lateral sclerosis

Examples of Lou Gehrig's disease in a Sentence

Recent Examples on the Web

Amyotrophic lateral sclerosis, also known as Lou Gehrig's disease, is a degenerative motor neuron disease. —Mars Salazar, Austin American Statesman, 27 Jan. 2026

Hawking’s work on the physics of black holes helped reshape the scientific understanding of the universe, even after being diagnosed with a motor neuron disease also known as ALS, or Lou Gehrig's disease, early in life that gradually paralyzed him. —Arizona Republic, AZCentral.com, 8 Jan. 2026

In April, Dane announced that he had been diagnosed with amyotrophic lateral sclerosis, which is also known as Lou Gehrig's disease. —Raechal Shewfelt, Entertainment Weekly, 8 Dec. 2025

Due to his amyotrophic lateral sclerosis, commonly known as Lou Gehrig's disease, Dane has lost use of his right arm. —Kimi Robinson, USA Today, 29 Sep. 2025

Word History

Etymology

Lou Gehrig †1941 American baseball player who suffered from the disease

First Known Use

1939, in the meaning defined above

Rhymes for Lou Gehrig's disease

• ferromanganese
• mephistopheles
• ostracods
• abcs
• absentees
• addressees
• adoptees
• allottees
• amputees
• antifreeze
• appellees
• appointees

Medical Definition

Lou Gehrig's disease

noun

Lou Geh·​rig's disease ˌlü-ˌge(ə)r-igz-, -ˌga(ə)r- 

: amyotrophic lateral sclerosis