graft-versus-host disease

noun

Definition of graft-versus-host disease

: a potentially fatal bodily condition that results when T cells from a tissue or organ transplant and especially a bone marrow transplant react immunologically against the recipient's antigens attacking cells and tissues

Examples of graft-versus-host disease in a Sentence

Recent Examples on the Web That means there is less risk of graft-versus-host disease or a rejection of the stem cells. AZCentral.com, 9 June 2021 Even five years ago, using a donor who was a half match was impossible because the risk of graft-versus-host disease was too high. Ginny Graves, Good Housekeeping, 17 Nov. 2020 The deal comes on the heels of the U.S. Food and Drug Administration telling the Australian drug developer in October that further study was needed before the agency would consider an approval in another ailment, graft-versus-host disease. Cristin Flanagan, Bloomberg.com, 20 Nov. 2020 If absolutely necessary, one of them could donate their marrow, thanks to recent advances that minimize graft-versus-host disease with half matches. Ginny Graves, Good Housekeeping, 17 Nov. 2020 In such cases, ruxolitinib has proved successful in interrupting the chain of events that leads graft-versus-host disease to develop into a cytokine storm. Mark Johnson, Milwaukee Journal Sentinel, 24 June 2020 There are other treatments used to prevent a cytokine storm in patients suffering from graft-versus-host disease. Mark Johnson, Milwaukee Journal Sentinel, 24 June 2020 These patients develop a complication called graft-versus-host disease, in which the donor marrow mistakes the patient's own cells for foreign invaders, and attacks them. Mark Johnson, Milwaukee Journal Sentinel, 24 June 2020 Beyond that, there are dozens of ongoing clinical trials for conditions ranging from schizophrenia to Crohn’s disease to graft-versus-host disease—not to mention the appearance of CBD in consumer products ranging from oils to coffee to tampons. Amber Dance, Scientific American, 14 Nov. 2019

These example sentences are selected automatically from various online news sources to reflect current usage of the word 'graft-versus-host disease.' Views expressed in the examples do not represent the opinion of Merriam-Webster or its editors. Send us feedback.

See More

First Known Use of graft-versus-host disease

1965, in the meaning defined above

Keep scrolling for more

Learn More About graft-versus-host disease

Time Traveler for graft-versus-host disease

Time Traveler

The first known use of graft-versus-host disease was in 1965

See more words from the same year

Dictionary Entries Near graft-versus-host disease

graftonite

graft-versus-host disease

grager

See More Nearby Entries 

Statistics for graft-versus-host disease

Last Updated

15 Jun 2021

Cite this Entry

“Graft-versus-host disease.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/graft-versus-host%20disease. Accessed 3 Aug. 2021.

Style: MLA
MLACheck Mark Icon ChicagoCheck Mark Icon APACheck Mark Icon Merriam-WebsterCheck Mark Icon

Keep scrolling for more

More Definitions for graft-versus-host disease

graft-versus-host disease

noun

Medical Definition of graft-versus-host disease

: a bodily condition that results when T cells from a usually allogeneic tissue or organ transplant and especially a bone marrow transplant react immunologically against the recipient's antigens attacking cells and tissues, that affects especially the skin, gastrointestinal tract, and liver with symptoms including skin rash, fever, diarrhea, liver dysfunction, abdominal pain, and anorexia, and that may be fatal abbreviation GVHD

called also graft-versus-host reaction

More from Merriam-Webster on graft-versus-host disease

Britannica.com: Encyclopedia article about graft-versus-host disease

WORD OF THE DAY

Test Your Vocabulary

Farm Idioms Quiz

  • cow coming home
  • What does 'poke' refer to in the expression 'pig in a poke'?
How Strong Is Your Vocabulary?

Test your vocabulary with our 10-question quiz!

TAKE THE QUIZ
 AlphaBear 2

Spell words. Make bears.

TAKE THE QUIZ
Love words? Need even more definitions?

Subscribe to America's largest dictionary and get thousands more definitions and advanced search—ad free!