graft-versus-host disease

noun
graft-ver·​sus-host disease | \ ˈgraft-ˌvər-səs-ˈhōst- How to pronounce graft-versus-host disease (audio) \

Definition of graft-versus-host disease

: a potentially fatal bodily condition that results when T cells from a tissue or organ transplant and especially a bone marrow transplant react immunologically against the recipient's antigens attacking cells and tissues

Examples of graft-versus-host disease in a Sentence

Recent Examples on the Web Above-average levels of these cells were also associated with better survival and less graft-versus-host disease in transplant patients. Kate Ann Markey, The Conversation, 13 July 2022 Up to 50% of patients who receive a stem cell transplant develop graft-versus-host disease. Kate Ann Markey, The Conversation, 13 July 2022 Patients with the highest levels of MAIT cells had the lowest incidence of graft-versus-host disease. Kate Ann Markey, The Conversation, 13 July 2022 Tinkov resigned as Tinkoff Bank’s chairman in 2020 after being diagnosed with acute leukemia and is battling graft-versus-host disease following a bone marrow transplant. Derek Saul, Forbes, 3 May 2022 The donor’s immune cells can attack the recipient’s body, a condition called graft-versus-host disease, or GVHD. Max G. Levy, Wired, 10 Feb. 2022 Dietrich Beelen, a transplant doctor at the University of Duisburg-Essen in Germany, was interested in using MSCs to treat a patient with severe graft-versus-host disease (GVHD). Michael Eisenstein, Scientific American, 17 June 2020 In July, Kadmon secured U.S. approval for Rezurock, a new treatment for chronic graft-versus-host disease — a debilitating immune condition that can affect as many as half of the blood cancer patients who undergo bone marrow transplants. Adam Feuerstein, STAT, 11 Sep. 2021 But finding a matching cell donor can be difficult, and a transplant can lead to graft-versus-host disease, a potentially deadly condition in which donor cells attack a patient’s cells. Kelly Servick, Science | AAAS, 11 Aug. 2021 See More

These example sentences are selected automatically from various online news sources to reflect current usage of the word 'graft-versus-host disease.' Views expressed in the examples do not represent the opinion of Merriam-Webster or its editors. Send us feedback.

First Known Use of graft-versus-host disease

1965, in the meaning defined above

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The first known use of graft-versus-host disease was in 1965

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graftonite

graft-versus-host disease

grager

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Last Updated

19 Sep 2022

Cite this Entry

“Graft-versus-host disease.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/graft-versus-host%20disease. Accessed 28 Sep. 2022.

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More Definitions for graft-versus-host disease

graft-versus-host disease

noun

Medical Definition of graft-versus-host disease

: a bodily condition that results when T cells from a usually allogeneic tissue or organ transplant and especially a bone marrow transplant react immunologically against the recipient's antigens attacking cells and tissues, that affects especially the skin, gastrointestinal tract, and liver with symptoms including skin rash, fever, diarrhea, liver dysfunction, abdominal pain, and anorexia, and that may be fatal abbreviation GVHD

called also graft-versus-host reaction

More from Merriam-Webster on graft-versus-host disease

Britannica.com: Encyclopedia article about graft-versus-host disease

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