graft-versus-host disease

noun

Definition of graft-versus-host disease 

: a potentially fatal bodily condition that results when T cells from a tissue or organ transplant and especially a bone marrow transplant react immunologically against the recipient's antigens attacking cells and tissues

Examples of graft-versus-host disease in a Sentence

Recent Examples on the Web

Unfortunately, the transplant triggered a rare form of chronic graft-versus-host disease, in which the donor's immune cells attack the recipient's normal cells. Sandee Lamotte, CNN, "Dogs bring 'a little light' into 'nightmare' of childhood cancer," 22 Dec. 2017

These example sentences are selected automatically from various online news sources to reflect current usage of the word 'graft-versus-host disease.' Views expressed in the examples do not represent the opinion of Merriam-Webster or its editors. Send us feedback.

First Known Use of graft-versus-host disease

1965, in the meaning defined above

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grafting tool

grafting wax

graftonite

graft-versus-host disease

grager

Graham

Graham's salt

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The first known use of graft-versus-host disease was in 1965

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graft-versus-host disease

noun

Medical Definition of graft-versus-host disease 

: a bodily condition that results when T cells from a usually allogeneic tissue or organ transplant and especially a bone marrow transplant react immunologically against the recipient's antigens attacking cells and tissues, that affects especially the skin, gastrointestinal tract, and liver with symptoms including skin rash, fever, diarrhea, liver dysfunction, abdominal pain, and anorexia, and that may be fatal abbreviation GVHD

called also graft-versus-host reaction

More from Merriam-Webster on graft-versus-host disease

Britannica.com: Encyclopedia article about graft-versus-host disease

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occurring twice a year or every two years

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