disease

noun

dis·​ease di-ˈzēz How to pronounce disease (audio)
Synonyms of diseasenext
1
: a condition of the living animal or plant body or of one of its parts that impairs normal functioning and is typically manifested by distinguishing signs and symptoms : sickness, malady
infectious diseases
a rare genetic disease
heart disease
2
: a harmful development (as in a social institution)
sees the city's crime as a disease
3
obsolete : trouble

Examples of disease in a Sentence

He suffers from a rare genetic disease. a disease of the mind Thousands die of heart disease each year. They are working to stop the spread of disease in rural areas. The article cites intolerance as one of the most dangerous of society's diseases. He sees crime as a disease that too often plagues the poor and disadvantaged.
Recent Examples on the Web
Examples are automatically compiled from online sources to show current usage. Read More Opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback.
If a fetus becomes infected, toxoplasmosis can lead to a range of health problems, including premature birth, low birth weight, jaundice or other liver problems, abnormal blood counts, rashes, eye disease, developmental delays, seizures, brain calcification, and in extreme cases, stillbirth. Dr. Megan Yanny, Boston Herald, 31 May 2026 At Camino del Molino (CMOL) in Spain, over 1,300 individuals were laid to rest, 5,000 years ago, because respiratory disease had become widespread, killing a significant number of individuals, who had been laid to rest in this circular gravesite carved into rock. Maria Mocerino, Interesting Engineering, 30 May 2026 Dogs that have a limited ability to control their body temperature — such as those with respiratory diseases, obese dogs and puppies — should never be left unattended in a vehicle, regardless of outside air temperature. The Washington Post, San Diego Union-Tribune, 30 May 2026 According to the Mayo Clinic, Lyme disease is an illness caused by borrelia bacteria, usually contracted by the bite of a tick carrying the bacteria. Tereza Shkurtaj, PEOPLE, 30 May 2026 See All Example Sentences for disease

Word History

Etymology

Middle English disese, from Anglo-French desease, desaise, from des- dis- + eise ease

First Known Use

14th century, in the meaning defined at sense 3

Time Traveler
The first known use of disease was in the 14th century

Browse Nearby Words

Cite this Entry

“Disease.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/disease. Accessed 31 May. 2026.

Kids Definition

disease

noun
dis·​ease diz-ˈēz How to pronounce disease (audio)
: an abnormal bodily condition of a living plant or animal that interferes with functioning and can usually be recognized by signs and symptoms : illness
diseased adjective

Medical Definition

disease

noun
dis·​ease diz-ˈēz How to pronounce disease (audio)
: an impairment of the normal state of the living animal or plant body or one of its parts that interrupts or modifies the performance of the vital functions, is typically manifested by distinguishing signs and symptoms, and is a response to environmental factors (as malnutrition, industrial hazards, or climate), to specific infective agents (as worms, bacteria, or viruses), to inherent defects of the organism (as genetic anomalies), or to combinations of these factors : sickness, illness

called also morbus

compare health sense 1
diseased adjective

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