refractoriness 1 of 2

refractory

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adjective

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Synonym Chooser

How does the adjective refractory differ from other similar words?

Some common synonyms of refractory are headstrong, intractable, recalcitrant, ungovernable, unruly, and willful. While all these words mean "not submissive to government or control," refractory stresses resistance to attempts to manage or to mold.

special schools for refractory children

When can headstrong be used instead of refractory?

The words headstrong and refractory can be used in similar contexts, but headstrong suggests self-will impatient of restraint, advice, or suggestion.

a headstrong young cavalry officer

Where would intractable be a reasonable alternative to refractory?

While in some cases nearly identical to refractory, intractable suggests stubborn resistance to guidance or control.

intractable opponents of the hazardous-waste dump

When would recalcitrant be a good substitute for refractory?

Although the words recalcitrant and refractory have much in common, recalcitrant suggests determined resistance to or defiance of authority.

acts of sabotage by a recalcitrant populace

In what contexts can ungovernable take the place of refractory?

The meanings of ungovernable and refractory largely overlap; however, ungovernable implies either an escape from control or guidance or a state of being unsubdued and incapable of controlling oneself or being controlled by others.

ungovernable rage

When is unruly a more appropriate choice than refractory?

The synonyms unruly and refractory are sometimes interchangeable, but unruly implies lack of discipline or incapacity for discipline and often connotes waywardness or turbulence of behavior.

unruly children

When could willful be used to replace refractory?

The words willful and refractory are synonyms, but do differ in nuance. Specifically, willful implies an obstinate determination to have one's own way.

a willful disregard for the rights of others

Example Sentences

Examples are automatically compiled from online sources to show current usage. Read More Opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback.
Recent Examples of refractoriness
Adjective
This current study extends the successful results previously published on the virus-free preparation of CD19-specific CAR T-cells against refractory B cell malignancies utilizing Applied DNA's Linea™ DNA. Kansas City Star, 13 May 2024 Marinus Pharmaceuticals said an experimental treatment for refractory status epilepticus failed to meet early stopping criteria for a Phase 3 study. Meghana Keshavan, STAT, 15 Apr. 2024 All of the children had rare, relapsed or refractory cancers and were running out of treatment options. Michelle Marchante, Miami Herald, 11 Apr. 2024 Many of those patients were able to receive a potentially curative stem cell transplant later on, which is often the ultimate goal for patients with relapsed or refractory patients. Damian Garde, STAT, 13 Dec. 2023 See All Example Sentences for refractoriness
Recent Examples of Synonyms for refractoriness
Noun
  • The light pink Rose Blossoming Set gives me a sense of femininity and calmness while the black Serpent dress gives me a feeling of rebellion and power.
    Rachel Elspeth Gross, Forbes.com, 15 June 2025
  • This cosmic synergy brings an equal amount of rebellion and shock, pushing you to break free from your comfort zone.
    Valerie Mesa, People.com, 14 June 2025
Adjective
  • Inspired by 1953’s The Wild One starring Marlon Brando, the song and video captures the rebellious spirit of the cult classic, with scenes of a motorcycle being driven on an open road and birds in flight.
    Althea Legaspi, Rolling Stone, 4 June 2025
  • Many historians estimate that at least 15 to 20 percent of the population remained loyal to the crown, some even taking up arms against their rebellious neighbors and fighting alongside the British.
    Greg Daugherty, Smithsonian Magazine, 4 June 2025
Adjective
  • Their relationship can be difficult as AM is stubborn and likes to have her way always.
    Carolyn Rosenblatt, Forbes.com, 9 June 2025
  • Some of these infections stop on their own, but others are too stubborn, or too serious, to leave untreated.
    Sam Walters, Discover Magazine, 4 June 2025
Noun
  • But general director Lawrence Edelson struck a note of defiance in his opening remarks on Friday, to cheers.
    Hannah Edgar, Chicago Tribune, 7 June 2025
  • The Maryland sheet metal worker was released from prison in El Salvador and put on a plane back to the U.S. two months after he was deported to his homeland in defiance of an order not to return him there for fear of persecution, ABC News first reported.
    Dave Goldiner, New York Daily News, 6 June 2025
Adjective
  • Yet none of this has dampened Mr. Trump’s enthusiasm for bringing U.S. influence to bear in trying to end the rebel incursion – in part because the fighting has affected a region that holds some of Congo’s main rare earth deposits.
    Ned Temko, Christian Science Monitor, 12 June 2025
  • The legislature entertained several bills—including two from Sumner—to authorize the government to seize rebel property, including slaves.
    Zaakir Tameez June 11, Literary Hub, 11 June 2025
Adjective
  • In response, these recalcitrant members of Congress simply refused to adopt must-pass federal reapportionment legislation.
    Made by History, Time, 2 Apr. 2025
  • Among Congressional Republicans, Paul has been more recalcitrant than most.
    Eric Cortellessa, TIME, 18 Mar. 2025
Adjective
  • Kim Kardashian made a defiant walk into Paris' Palace of Justice in May, to face the criminals who held the reality star at gunpoint and robbed in 2016.
    Doc Louallen, ABC News, 6 June 2025
  • In an era defined by digital speed, algorithmic curation, and disposable listening, Gearbox Records has carved out a defiant space for intentionality, sonic depth, and analog fidelity.
    Steve Baltin, Forbes.com, 5 June 2025
Adjective
  • These organizations see quantum computers as complementary accelerators that could help address intractable problems that classical machines cannot realistically solve.
    Yuval Boger, Forbes.com, 9 June 2025
  • Perhaps, some mused, the same collaborative spirit could be harnessed to tackle other intractable problems, like a severe housing crisis and corrosive inequality.
    Rachel Morris, New Yorker, 5 June 2025

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Cite this Entry

“Refractoriness.” Merriam-Webster.com Thesaurus, Merriam-Webster, https://www.merriam-webster.com/thesaurus/refractoriness. Accessed 20 Jun. 2025.

Last Updated: - Updated example sentences
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