incapacitate

1 to render powerless, ineffective, or unable to move the malfunctioning of a single component can incapacitate the engine Synonyms cripple, disable, hamstring, immobilize, paralyze, prostrateRelated Words attenuate, debilitate, enervate, enfeeble, sap, tire, undercut, undermine, weaken; hobble, lame; maim, mutilate; knock outNear Antonyms energize, galvanize, invigorate, vitalize; fortify, strengthen; empower; freshen, refresh, refreshen, regenerate, rejuvenate, restore, revitalize, revive

2 to cause severe or permanent injury to the stroke left her completely incapacitated Synonyms cripple, disable, maim, lame, mutilateRelated Words dismember, hamstring, hobble, paralyze; batter, bruise, bung up, mangle, maul, rough (up); gore, lacerate, wing, wound; disfigure, scar; kneecap; break, damage, harm, hurt, impair, injure; bash, beat, belt, bludgeon, buffet, drub, hammer, lace, lambaste (or lambast), lick, paste, pelt, pommel, pound, pummel, thump; bang, box, hit, punch, slap, smack, smash, sock, spank, swat, swipe, thrash, thwack, whack; flog, lash, wallop, whip; kill, murder; torment, tortureNear Antonyms cure, heal, rehabilitate, remedy; doctor, fix, mend, patch; rejuvenate, renew, repair, restore