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Synonym Chooser

How does the adjective refractory differ from other similar words?

Some common synonyms of refractory are headstrong, intractable, recalcitrant, ungovernable, unruly, and willful. While all these words mean "not submissive to government or control," refractory stresses resistance to attempts to manage or to mold.

special schools for refractory children

When can headstrong be used instead of refractory?

The words headstrong and refractory can be used in similar contexts, but headstrong suggests self-will impatient of restraint, advice, or suggestion.

a headstrong young cavalry officer

Where would intractable be a reasonable alternative to refractory?

While in some cases nearly identical to refractory, intractable suggests stubborn resistance to guidance or control.

intractable opponents of the hazardous-waste dump

When would recalcitrant be a good substitute for refractory?

Although the words recalcitrant and refractory have much in common, recalcitrant suggests determined resistance to or defiance of authority.

acts of sabotage by a recalcitrant populace

In what contexts can ungovernable take the place of refractory?

The meanings of ungovernable and refractory largely overlap; however, ungovernable implies either an escape from control or guidance or a state of being unsubdued and incapable of controlling oneself or being controlled by others.

ungovernable rage

When is unruly a more appropriate choice than refractory?

The synonyms unruly and refractory are sometimes interchangeable, but unruly implies lack of discipline or incapacity for discipline and often connotes waywardness or turbulence of behavior.

unruly children

When could willful be used to replace refractory?

The words willful and refractory are synonyms, but do differ in nuance. Specifically, willful implies an obstinate determination to have one's own way.

a willful disregard for the rights of others

Example Sentences

Examples are automatically compiled from online sources to show current usage. Read More Opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback.
Recent Examples of refractory It is meant to treat only people with refractory myeloma. Sarah Hudgens, Health, 23 Sep. 2024 Similar to refractory bricks, firebricks can store heat or insulate, depending on what they’re made from. New Atlas, 5 Aug. 2024 This current study extends the successful results previously published on the virus-free preparation of CD19-specific CAR T-cells against refractory B cell malignancies utilizing Applied DNA's Linea™ DNA. Kansas City Star, 13 May 2024 Marinus Pharmaceuticals said an experimental treatment for refractory status epilepticus failed to meet early stopping criteria for a Phase 3 study. Meghana Keshavan, STAT, 15 Apr. 2024 See All Example Sentences for refractory
Recent Examples of Synonyms for refractory
Adjective
  • Silicon Valley definitely has so much of that rebellious spirit.
    Andre Byik, USA Today, 10 Nov. 2025
  • On Tracker, Ackles portrays Russell, Colter’s charismatic and rebellious older brother, who has a similar skill set and lack of stable home life.
    Katie Mannion, PEOPLE, 9 Nov. 2025
Adjective
  • That tone—of pain, of surprise, of a stubborn refusal to be reduced or diminished—is everywhere in it.
    Questlove, The Atlantic, 7 Nov. 2025
  • If the stain is stubborn, add a few drops of dish soap to the water and vinegar mixture.
    Ashlyn Needham, Southern Living, 7 Nov. 2025
Adjective
  • Al-Sharaa led the rebel forces that toppled former Syrian President Bashar Assad last December and was named the country's interim leader in January.
    NPR, NPR, 11 Nov. 2025
  • Warriors from more than a dozen Native nations in the trans-Appalachian West helped the redcoats engage rebel forces, as did perhaps twenty-five thousand Black fugitives from slavery.
    Literary Hub, Literary Hub, 7 Nov. 2025
Adjective
  • During the Obama and Biden administrations, the US used its bully pulpit to drag more recalcitrant countries like China and the Gulf petrostates to the table and sign them on to promises to cut carbon and shell out cash to help poorer countries.
    Tim McDonnell, semafor.com, 6 Nov. 2025
  • The president’s biggest tool has been his willingness to impose high tariffs or punitive sanctions on the recalcitrant parties, showing that the United States’ vast economic power can be as useful as its military might in ending sticky conflicts.
    Robert C. O’Brien, Foreign Affairs, 5 Nov. 2025
Adjective
  • Cushla’s world is full of defiant spirits, including her mother, a woman struggling with addiction who spends most of her days bound to her living room and the bottom of a bottle.
    Max Goldbart, Deadline, 5 Nov. 2025
  • The mayor-elect was defiant in his victory speech.
    Sydney Lake, Fortune, 5 Nov. 2025
Adjective
  • Among the recurrent themes are suicide, mysteriously intractable sorrow, and failed attempts at familial and romantic connection.
    Margaret Talbot, New Yorker, 3 Nov. 2025
  • The open-source project has been used by millions of scientists in more than 190 countries, accelerating research into diseases previously considered intractable.
    Dave Smith, Fortune, 26 Oct. 2025
Adjective
  • Newsom said that by sending California Guard members to Oregon and Illinois the administration is essentially admitting that they are not needed in Los Angeles, where the immigration officials they were sent to protect have not faced violent or uncontrollable protests for months.
    Sharon Bernstein, Sacbee.com, 3 Nov. 2025
  • The cough grew violent, uncontrollable and exhausting.
    Ashley Vega, PEOPLE, 27 Oct. 2025
Adjective
  • On Friday, a federal judge shot down arguments that the emergency funds can be employed only for hurricanes or other unmanageable catastrophes, ruling in favor of more than 20 states led by Democrats that sued the administration.
    Tara Suter, The Hill, 2 Nov. 2025
  • The Humane Society reminds pet owners that help is available for those feeling overwhelmed and encourages community members to reach out before situations become unmanageable.
    Moná Thomas, PEOPLE, 29 Oct. 2025

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Cite this Entry

“Refractory.” Merriam-Webster.com Thesaurus, Merriam-Webster, https://www.merriam-webster.com/thesaurus/refractory. Accessed 18 Nov. 2025.

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