Definition of refractorynext
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Synonym Chooser

How does the adjective refractory differ from other similar words?

Some common synonyms of refractory are headstrong, intractable, recalcitrant, ungovernable, unruly, and willful. While all these words mean "not submissive to government or control," refractory stresses resistance to attempts to manage or to mold.

special schools for refractory children

When can headstrong be used instead of refractory?

The words headstrong and refractory can be used in similar contexts, but headstrong suggests self-will impatient of restraint, advice, or suggestion.

a headstrong young cavalry officer

Where would intractable be a reasonable alternative to refractory?

While in some cases nearly identical to refractory, intractable suggests stubborn resistance to guidance or control.

intractable opponents of the hazardous-waste dump

When would recalcitrant be a good substitute for refractory?

Although the words recalcitrant and refractory have much in common, recalcitrant suggests determined resistance to or defiance of authority.

acts of sabotage by a recalcitrant populace

In what contexts can ungovernable take the place of refractory?

The meanings of ungovernable and refractory largely overlap; however, ungovernable implies either an escape from control or guidance or a state of being unsubdued and incapable of controlling oneself or being controlled by others.

ungovernable rage

When is unruly a more appropriate choice than refractory?

The synonyms unruly and refractory are sometimes interchangeable, but unruly implies lack of discipline or incapacity for discipline and often connotes waywardness or turbulence of behavior.

unruly children

When could willful be used to replace refractory?

The words willful and refractory are synonyms, but do differ in nuance. Specifically, willful implies an obstinate determination to have one's own way.

a willful disregard for the rights of others

Example Sentences

Examples are automatically compiled from online sources to show current usage. Read More Opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback.
Recent Examples of refractory It is meant to treat only people with refractory myeloma. Sarah Hudgens, Health, 23 Sep. 2024 Similar to refractory bricks, firebricks can store heat or insulate, depending on what they’re made from. New Atlas, 5 Aug. 2024 This current study extends the successful results previously published on the virus-free preparation of CD19-specific CAR T-cells against refractory B cell malignancies utilizing Applied DNA's Linea™ DNA. Kansas City Star, 13 May 2024 Marinus Pharmaceuticals said an experimental treatment for refractory status epilepticus failed to meet early stopping criteria for a Phase 3 study. Meghana Keshavan, STAT, 15 Apr. 2024 See All Example Sentences for refractory
Recent Examples of Synonyms for refractory
Adjective
  • Prior to the Emancipation Proclamation, slavery was the law in the rebellious states.
    Doug Ross, Chicago Tribune, 3 Jan. 2026
  • This wretched regime is doomed to be overthrown by the risen populace and rebellious youth.
    Efrat Lachter, FOXNews.com, 1 Jan. 2026
Adjective
  • That tone—of pain, of surprise, of a stubborn refusal to be reduced or diminished—is everywhere in it.
    Questlove, The Atlantic, 7 Nov. 2025
  • If the stain is stubborn, add a few drops of dish soap to the water and vinegar mixture.
    Ashlyn Needham, Southern Living, 7 Nov. 2025
Adjective
  • Two men are targeted by the rebel army who overthrew the government of Colonel Jacobo Arbenz Guzman.
    CBS News, CBS News, 3 Jan. 2026
  • He was denounced by rebel propagandists as a tyrant and remembered by Americans as a reactionary dolt.
    Bhumika Tharoor, The Atlantic, 30 Dec. 2025
Adjective
  • Adams had carefully shepherded it through an often-recalcitrant City Council and through the gauntlet of demands coming from both the real estate lobby and pro-housing advocates.
    New York Daily News Editorial Board, New York Daily News, 1 Jan. 2026
  • Putin has been recalcitrant about accepting previous Trump plans to end the war.
    Benjamin Weinthal, FOXNews.com, 27 Nov. 2025
Adjective
  • Vice President Delcy Rodriguez initially was angry and defiant.
    Arthur I. Cyr, Chicago Tribune, 6 Jan. 2026
  • Venezuela’s interim leader, Vice President Delcy Rodríguez, has alternated between taking a conciliatory approach towards Washington and striking a defiant tone.
    Prashant Rao, semafor.com, 5 Jan. 2026
Adjective
  • Among the recurrent themes are suicide, mysteriously intractable sorrow, and failed attempts at familial and romantic connection.
    Margaret Talbot, New Yorker, 3 Nov. 2025
  • The open-source project has been used by millions of scientists in more than 190 countries, accelerating research into diseases previously considered intractable.
    Dave Smith, Fortune, 26 Oct. 2025
Adjective
  • Leaders often blame uncontrollable factors—policies of previous administrations, hiring for a boom that fizzled unexpectedly, macroeconomic uncertainty, the rise of artificial intelligence—but all too often the real strategic issues go unaddressed.
    Harvard Business Review, Harvard Business Review, 1 Jan. 2026
  • The phenomenon of cavitation—the formation and collapse of tiny gas bubbles due to changes in pressure—was considered an undesirable and largely uncontrollable side effect.
    IEEE Spectrum, IEEE Spectrum, 22 Dec. 2025
Adjective
  • On Friday, a federal judge shot down arguments that the emergency funds can be employed only for hurricanes or other unmanageable catastrophes, ruling in favor of more than 20 states led by Democrats that sued the administration.
    Tara Suter, The Hill, 2 Nov. 2025
  • The Humane Society reminds pet owners that help is available for those feeling overwhelmed and encourages community members to reach out before situations become unmanageable.
    Moná Thomas, PEOPLE, 29 Oct. 2025

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Cite this Entry

“Refractory.” Merriam-Webster.com Thesaurus, Merriam-Webster, https://www.merriam-webster.com/thesaurus/refractory. Accessed 10 Jan. 2026.

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