LOCO Synonyms: 124 Similar and Opposite Words

loco 1 of 2

adjective

Definition of loco

slang

as in psychotic

unable to think in a clear or sensible way that dog's straight loco, just running around in circles all day long

Synonyms & Similar Words

Relevance

Antonyms & Near Antonyms

loco

2 of 2

verb

as in to bother

to cause to go insane or as if insane years of living alone had clearly locoed the old rancher

Synonyms & Similar Words

Antonyms & Near Antonyms

Example Sentences

Examples are automatically compiled from online sources to show current usage. Read More Opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback.

Recent Examples of loco

Adjective

Real investors survey the landscape and look for signs of a market gone loco. — Andy Kessler, WSJ, 2 July 2017

Recent Examples of Synonyms for loco

Adjective

Unfortunately, his doctor interprets all the screaming about an alien presence in Thomas’ head as a garden-variety psychotic breakdown, and remands him to a more secure facility.

— Tasha Robinson, Vulture, 14 Oct. 2026
It may also be used to treat certain other psychotic conditions, such as psychosis arising in Parkinson disease.

— Encyclopedia Britannica, Encyclopedia Britannica, 7 Oct. 2026

Definition of psychotic

Verb

Gee, who used to pop into fraternity parties unannounced to keep tabs on them, said he is not bothered by the reintegration of the three formerly rogue organizations.

— Brittany Shammas, CNN Money, 17 Oct. 2026
This is a dense picture—there’s almost too much to unpack, if you can be bothered to care about any of it.

— Stephanie Zacharek, Time, 16 Oct. 2026

Definition of bother

Adjective

Richard Dawkins, the British evolutionary theorist and author of the groundbreaking best seller The Selfish Gene (1976), among many other books, appears to have gone a bit mad.

— James Gleick, The New York Review of Books, 17 Oct. 2026
Mel Brooks’ comedy The Producers also took a poke at that mad man with Springtime for Hitler.

— Angie Martoccio, Rolling Stone, 15 Oct. 2026

Definition of mad

Verb

Denying the Wave a crucial 1-0 lead, no teammate could convert on a bright drive and dish by speedster Ludmila that unbalanced Seattle’s defense.

— Tom Krasovic, San Diego Union-Tribune, 27 July 2026
The risk is that only a handful of clubs will be able to cough up those sums, unbalancing the market.

— Charlotte Harpur, New York Times, 19 May 2026

Definition of unbalance

Adjective

First and foremost, as a homeowner myself the property taxes are insane and continue to go up.

— Stephen Korka, Sun Sentinel, 13 Oct. 2026
That may be the name of her next album, but Venus’ insane popularity also speaks to the way Metropia is moving forward, constantly looking for the next shiny thing.

— Kate Erbland, IndieWire, 10 Oct. 2026

Definition of insane

Verb

From SheetsGate to purposefully washing Joy’s uniforms with rags, the laundry room has unleashed something deranged in Gen.

— Rafaela Bassili, Vulture, 22 Sep. 2026
Featuring an ensemble populated by killer character actors like Jacki Weaver, Luis Guzmán, Kurtwood Smith, Timothy Spall, and Michael Chernus, Perpetual Grace, LTD is an off-kilter neo-noir that mines deranged humor from its eccentric characters.

— Britt Hayes, Entertainment Weekly, 7 Aug. 2026

Definition of derange

Adjective

Rihanna’s here, maniacal crowds are lining up outside shows to screech and wave at their favorite stars and days of runway events big and small lie ahead.

— Leah Dolan, CNN Money, 30 Sep. 2026
These machines—the maniacal Maverick R, with its praying mantis-like front suspension, and the hard-working Pioneer—have little else in common.

— Caleb Jacobs, The Drive, 2 Sep. 2026

Definition of maniacal

Browse Nearby Words

lockups

loco

locoed

See all Nearby Words

Cite this Entry

Style

“Loco.” Merriam-Webster.com Thesaurus, Merriam-Webster, https://www.merriam-webster.com/thesaurus/loco. Accessed 20 Oct. 2026.

Copy Citation

Synonyms of loco

adjective

verb

Example Sentences

Browse Nearby Words

Cite this Entry

More from Merriam-Webster

Word of the Day

compunction

Popular in Grammar & Usage

Merriam-Webster’s Great Big List of Words You Love to Hate

'Can' vs. 'May'

'Affect' vs. 'Effect'

More Commonly Mispronounced Words

Is it 'nerve-racking' or 'nerve-wracking'?

Popular in Wordplay

The Longest Long Words List

9 Words That Sound Like Insults But Aren't

Did 'orange' the fruit or the color come first?

Even More Bird Names that Sound Like Insults (and Sometimes Are)

12 Lovely and Unusual Words for the Natural World

Popular

Merriam-Webster’s Great Big List of Words You Love to Hate

The Longest Long Words List

9 Words That Sound Like Insults But Aren't

Games & Quizzes