PSYCHO Synonyms: 96 Similar and Opposite Words

psycho

adjective

Definition of psycho

informal + disparaging

as in psychotic

unable to think in a clear or sensible way Only someone who is totally psycho could have committed such a heinous crime.

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Example Sentences

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Recent Examples of psycho Which is psycho, absolutely psycho. — Ryan Coleman, Entertainment Weekly, 27 May 2026 The key figure turns out to be Alex’s mysterious Aunt Gladys, played in full psycho-biddy drag by Amy Madigan. — Louis Peitzman, Vulture, 8 Aug. 2025

Recent Examples of Synonyms for psycho

Adjective

Unfortunately, his doctor interprets all the screaming about an alien presence in Thomas’ head as a garden-variety psychotic breakdown, and remands him to a more secure facility.

— Tasha Robinson, Vulture, 14 Oct. 2026
It may also be used to treat certain other psychotic conditions, such as psychosis arising in Parkinson disease.

— Encyclopedia Britannica, Encyclopedia Britannica, 7 Oct. 2026

Definition of psychotic

Adjective

Richard Dawkins, the British evolutionary theorist and author of the groundbreaking best seller The Selfish Gene (1976), among many other books, appears to have gone a bit mad.

— James Gleick, The New York Review of Books, 17 Oct. 2026
Mel Brooks’ comedy The Producers also took a poke at that mad man with Springtime for Hitler.

— Angie Martoccio, Rolling Stone, 15 Oct. 2026

Definition of mad

Adjective

Rihanna’s here, maniacal crowds are lining up outside shows to screech and wave at their favorite stars and days of runway events big and small lie ahead.

— Leah Dolan, CNN Money, 30 Sep. 2026
These machines—the maniacal Maverick R, with its praying mantis-like front suspension, and the hard-working Pioneer—have little else in common.

— Caleb Jacobs, The Drive, 2 Sep. 2026

Definition of maniacal

Adjective

The mental toll that comes with Ebola Losing relatives to disease outbreaks is always difficult, but responders say grief can be especially severe with Ebola in a country where the disease is viewed by many as evil due to rumors and misconceptions.

— Constant Same Bagalwa, Los Angeles Times, 21 Oct. 2026
Their alluring quality belies their extreme toxicity; at times used as a hallucinogen, their ingestion can cause severe mental confusion and even death.

— Tatiane de Assis, ARTnews.com, 21 Oct. 2026