syndrome

noun

syn·​drome ˈsin-ˌdrōm 

also

-drəm 

1

: a group of signs and symptoms that occur together and characterize a particular abnormality or condition

2

: a set of concurrent things (such as emotions or actions) that usually form an identifiable pattern

Did you know?

Combining its two Greek roots, syndrome means basically "running together". So when diagnosing a condition or disease, doctors tend to look for a group of symptoms existing together. As long as a set of symptoms remains mysterious, it may be referred to as a specific syndrome. But if that name is used for a while, it may become the condition's permanent name, even after an underlying cause has been found. So today we have Down syndrome, acquired immune deficiency syndrome, Asperger's syndrome, carpal tunnel syndrome, chronic fatigue syndrome, Tourette's syndrome, sick building syndrome, and many more. And since mental conditions often turn out to have physical causes, syndrome is used in psychology as well as in medicine.

Examples of syndrome in a Sentence

Recent Examples on the Web

In 2022, the Canadian singer-songwriter shared she had been diagnosed with stiff-person syndrome, a neurological disorder that can cause muscle spasms. —Anna Kaufman, USA Today, 31 Mar. 2026

This population crisis feeds into a post-imperial syndrome, where the decline of empire and power status invokes a sense of loss of self-importance that gives rise to resentment and an unwavering commitment to retain great power status. —John Rennie Short, The Conversation, 31 Mar. 2026

Most cases caught early are treated effectively with antibiotics, but some patients have longer-lasting and sometimes devastating symptoms even after treatment, a condition referred to as post-treatment Lyme disease syndrome, or chronic or long Lyme. —Meg Tirrell, CNN Money, 31 Mar. 2026

In 2022, Dion announced she had been diagnosed with stiff person syndrome, known as SPS, a rare neurological disorder. —Ryan Brennan, Miami Herald, 31 Mar. 2026

Word History

Etymology

New Latin, from Greek syndromē combination, syndrome, from syn- + dramein to run — more at dromedary

First Known Use

1541, in the meaning defined at sense 1

Phrases Containing syndrome

• acquired immune deficiency syndrome
• acquired immunodeficiency syndrome
• acute respiratory distress syndrome
• adult respiratory distress syndrome
• androgen insensitivity syndrome
• Asperger's syndrome
• Asperger syndrome
• bashful bladder syndrome
• battered child syndrome
• battered woman syndrome
• carpal tunnel syndrome
• Chinese restaurant syndrome
• chronic fatigue syndrome
• complex regional pain syndrome
• Cushing's syndrome
• cytokine release syndrome
• cytokine storm syndrome
• Down's syndrome
• Down syndrome
• empty-nest syndrome
• fetal alcohol syndrome
• fragile X syndrome
• Guillain-Barré syndrome
• Gulf War syndrome
• Havana syndrome
• hemolytic uremic syndrome
• imposter syndrome
• impostor syndrome
• insulin resistance syndrome
• irritable bowel syndrome
• Kawasaki's syndrome
• Kawasaki syndrome
• Klinefelter's syndrome
• Marfan's syndrome
• Marfan syndrome
• metabolic syndrome
• Ménière's syndrome
• mucocutaneous lymph node syndrome
• multisystem inflammatory syndrome
• multisystem inflammatory syndrome in children
• Munchausen's syndrome
• Munchausen's syndrome by proxy
• Munchausen syndrome
• Munchausen syndrome by proxy
• nephrotic syndrome
• organic brain syndrome
• Parkinson's syndrome
• pediatric multisystem inflammatory syndrome
• polycystic ovary syndrome
• post-acute COVID-19 syndrome
• post-COVID-19 syndrome
• post-polio syndrome
• Prader-Willi syndrome
• premenstrual syndrome
• punch-drunk syndrome
• refeeding syndrome
• Reiter's syndrome
• respiratory distress syndrome
• restless legs syndrome
• Reye's syndrome
• savant syndrome
• severe acute respiratory syndrome
• shy bladder syndrome
• sick building syndrome
• Stockholm syndrome
• sudden infant death syndrome
• testicular feminization syndrome
• thoracic outlet syndrome
• Tourette's syndrome
• Tourette syndrome
• toxic shock syndrome
• Turner's syndrome
• white-coat syndrome
• Williams syndrome

Rhymes for syndrome

• biome
• genome
• megohm
• nichrome
• noisome
• prodrome
• radome
• rhizome
• shalom
• acrosome
• aerodrome
• catacomb

Kids Definition

syndrome

noun

syn·​drome ˈsin-ˌdrōm 

: a group of signs and symptoms that occur together and characterize a particular abnormality or condition

Medical Definition

syndrome

noun

syn·​drome

ˈsin-ˌdrōm also -drəm

: a group of signs and symptoms that occur together and characterize a particular abnormality