Definition of Cushing's syndrome
:an abnormal condition caused by excess levels of corticosteroids and especially cortisol in the body due either to hyperfunction of the adrenal gland (as from adrenal adenoma or hypersecretion of ACTH by the pituitary gland) or to prolonged use of corticosteroid medications (such as prednisone) and that is characterized by a variety of signs and symptoms including a full, rounded face with plethora, fatty deposits in the face, neck, and upper back, truncal obesity, easy bruising, fatigue, muscle weakness, and hypertension — see Cushing's disease
