Cushing's syndrome

noun

Definition of Cushing's syndrome

: an abnormal condition caused by excess levels of corticosteroids and especially cortisol in the body due either to hyperfunction of the adrenal gland (as from adrenal adenoma or hypersecretion of ACTH by the pituitary gland) or to prolonged use of corticosteroid medications (such as prednisone) and that is characterized by a variety of signs and symptoms including a full, rounded face with plethora, fatty deposits in the face, neck, and upper back, truncal obesity, easy bruising, fatigue, muscle weakness, and hypertension — see Cushing's disease

First Known Use of Cushing's syndrome

1937, in the meaning defined above

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The first known use of Cushing's syndrome was in 1937

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Dictionary Entries Near Cushing's syndrome

Cushing's disease

Cushing's syndrome

cushion

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Cite this Entry

“Cushing's syndrome.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/Cushing%27s%20syndrome. Accessed 16 May. 2022.

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More Definitions for Cushing's syndrome

Cushing's syndrome

noun

Medical Definition of Cushing's syndrome

: an abnormal condition caused by excess levels of corticosteroids and especially cortisol in the body due either to hyperfunction of the adrenal gland (as from adrenal adenoma or hypersecretion of ACTH by the pituitary gland) or to prolonged use of corticosteroid medications (as prednisone) and that is characterized by a variety of signs and symptoms including a change in appearance marked by moon face with plethora and truncal obesity, easy bruising, fatigue, muscle weakness, and hypertension

called also adrenogenital syndrome

— compare cushing's disease, hyperadrenocorticism

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