nu·​cle·​o·​some | \ ˈnü-klē-ə-ˌsōm How to pronounce nucleosome (audio) , ˈnyü- \

Definition of nucleosome

: any of the repeating globular subunits of chromatin that consist of a complex of DNA and histone

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Other Words from nucleosome

nucleosomal \ ˌnü-​klē-​ə-​ˈsō-​məl How to pronounce nucleosome (audio) , ˌnyü-​ \ adjective

Examples of nucleosome in a Sentence

Recent Examples on the Web Chromatin is built when DNA winds around millions of spool-like protein structures called nucleosomes. Quanta Magazine, "Genetic Geometry Takes Shape," 25 Feb. 2015

These example sentences are selected automatically from various online news sources to reflect current usage of the word 'nucleosome.' Views expressed in the examples do not represent the opinion of Merriam-Webster or its editors. Send us feedback.

First Known Use of nucleosome

1962, in the meaning defined above

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The first known use of nucleosome was in 1962

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Cite this Entry

“Nucleosome.” Dictionary, Merriam-Webster, Accessed 10 Apr. 2021.

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nu·​cleo·​some | \ -ˌsōm How to pronounce nucleosome (audio) \

Medical Definition of nucleosome

: any of the repeating globular subunits of chromatin that consist of a complex of DNA and histone and are thought to be present only during interphase

Other Words from nucleosome

nucleosomal \ ˌn(y)ü-​klē-​ə-​ˈsō-​məl How to pronounce nucleosome (audio) \ adjective

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