mi·​cro·​tome | \ ˈmī-krə-ˌtōm How to pronounce microtome (audio) \

Definition of microtome

: an instrument for cutting sections (as of biological tissues) for microscopic examination

Examples of microtome in a Sentence

Recent Examples on the Web Embryonic tissue was too delicate to withstand pressure from the clasp of a microtome. Benjamin Ehrlich, Scientific American, 21 Mar. 2022 As a journalist and novelist, Tom Wolfe could, like no one else, take one particular broad subject — class and status — and slice it thin for examination and diagnosis, like a pathologist with a microtome. Christopher Bonanos, Daily Intelligencer, 15 May 2018 Then, using a special instrument, a microtome, the technician would slice the paraffin block into ultrathin sections, about 0.0002 inches thick. Lynne Parenti, Smithsonian, 14 Mar. 2018

These example sentences are selected automatically from various online news sources to reflect current usage of the word 'microtome.' Views expressed in the examples do not represent the opinion of Merriam-Webster or its editors. Send us feedback.

First Known Use of microtome

1856, in the meaning defined above

History and Etymology for microtome

International Scientific Vocabulary

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The first known use of microtome was in 1856

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Cite this Entry

“Microtome.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/microtome. Accessed 2 Oct. 2022.

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More Definitions for microtome


mi·​cro·​tome | \ ˈmī-krə-ˌtōm How to pronounce microtome (audio) \

Medical Definition of microtome

 (Entry 1 of 2)

: an instrument for cutting sections (as of organic tissues) for microscopic examination bone-sectioning microtomes


transitive verb
microtomed; microtoming

Medical Definition of microtome (Entry 2 of 2)

: to cut in sections with a microtome

More from Merriam-Webster on microtome

Britannica.com: Encyclopedia article about microtome


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