cortisol

noun

cor·​ti·​sol ˈkȯr-tə-ˌsȯl 

-ˌzȯl,

-ˌsōl,

-ˌzōl

: a glucocorticoid C₂₁H₃₀O₅ produced by the adrenal cortex upon stimulation by ACTH that mediates various metabolic processes (such as gluconeogenesis), has anti-inflammatory and immunosuppressive properties, and whose levels in the blood may become elevated in response to physical or psychological stress

called also hydrocortisone

Examples of cortisol in a Sentence

Recent Examples on the Web

High temperatures can also negatively impact the quality and quantity of sleep, which can raise levels of cortisol in the body. —Mary Kekatos, ABC News, 16 July 2024

Elevated cortisol levels can lead to a decrease in testosterone, further affecting libido. —Dr. Jamin Brahmbhatt, CNN, 9 July 2024

The main hormone involved in the stress response – cortisol in humans and corticosterone in rodents, both abbreviated to CORT – is primarily a metabolic hormone, meaning that increasing blood levels of these hormones during stressful conditions results in more energy mobilized from fat stores. —Natalie C. Tronson, The Conversation, 24 June 2024

Some studies suggest that TTX may also serve as a stress reliever, which lowers levels of hormones like cortisol, making the fish less aggressive and promoting growth. —Brian Handwerk, Smithsonian Magazine, 12 June 2024

Word History

Etymology

cortisone + -ol entry 1

First Known Use

1951, in the meaning defined above

Medical Definition

cortisol

noun

cor·​ti·​sol ˈkȯrt-ə-ˌsȯl, -ˌzȯl, -ˌsōl, -ˌzōl 

: a glucocorticoid C₂₁H₃₀O₅ produced by the adrenal cortex upon stimulation by ACTH that mediates various metabolic processes (as gluconeogenesis), has anti-inflammatory and immunosuppressive properties, and whose levels in the blood may become elevated in response to physical or psychological stress

called also hydrocortisone