cor·​ti·​sone ˈkȯr-tə-ˌsōn How to pronounce cortisone (audio)
: a glucocorticoid C21H28O5 of the adrenal cortex used in synthetic form especially as an anti-inflammatory agent (as for rheumatoid arthritis)

Examples of cortisone in a Sentence

Recent Examples on the Web Other topical options for mild cases include cortisones and vitamin D creams, Zeichner says. Kelly Dougher, Allure, 21 Nov. 2023 What is the difference between cortisone and hydrocortisone? Danielle Zoellner, Verywell Health, 5 Oct. 2023 One of his patients recently traveled from Italy to get nothing more than a cortisone injection in the hip. Constant Méheut, New York Times, 14 Nov. 2023 Over-the-counter cortisone cream can help alleviate symptoms, but do not scratch or pick the lesions since that can cause further infection, Dr. Jacobs adds. Andi Breitowich, Women's Health, 8 Sep. 2023 Taking oral antihistamines and applying a topical steroid cream like cortisone can counter the itching associated with both eczema and psoriasis. Glamour, 7 Nov. 2022 A week after suffering a right rib cartilage fracture Aug. 13 in Toronto, Stroman received a cortisone shot. Meghan Montemurro, Chicago Tribune, 15 Sep. 2023 For the next several months, Helfer was treated with cortisone shots on her bald spots. Vanessa Etienne, Peoplemag, 15 Sep. 2023 Kershaw was given a cortisone shot and was only supposed to miss a couple of weeks. Bill Plaschke, Los Angeles Times, 11 Aug. 2023 See More

These examples are programmatically compiled from various online sources to illustrate current usage of the word 'cortisone.' Any opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback about these examples.

Word History


alteration of corticosterone

First Known Use

1949, in the meaning defined above

Time Traveler
The first known use of cortisone was in 1949

Dictionary Entries Near cortisone

Cite this Entry

“Cortisone.” Dictionary, Merriam-Webster, Accessed 6 Dec. 2023.

Kids Definition


cor·​ti·​sone ˈkȯrt-ə-ˌsōn How to pronounce cortisone (audio)
: a hormone of the adrenal glands that is used especially to reduce inflammation (as in the treatment of arthritis)

Medical Definition


cor·​ti·​sone -ˌsōn, -ˌzōn How to pronounce cortisone (audio)
: a glucocorticoid C21H28O5 that is produced naturally in small amounts by the adrenal cortex and is administered in the form of its synthetic acetate C23H30O6 especially as replacement therapy for deficient adrenocortical secretion and as an anti-inflammatory agent (as for rheumatoid arthritis) compare 11-dehydrocorticosterone

More from Merriam-Webster on cortisone

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