cor·​ti·​sone | \ ˈkȯr-tə-ˌsōn How to pronounce cortisone (audio) , -ˌzōn \

Definition of cortisone

: a glucocorticoid C21H28O5 of the adrenal cortex used in synthetic form especially as an anti-inflammatory agent (as for rheumatoid arthritis)

Examples of cortisone in a Sentence

Recent Examples on the Web They're tried everything — cortisone shots, New Balance sneakers, and inserts — to no avail. Amy Schulman,, 2 Apr. 2022 One of the effects of cortisone is to oppose the action of insulin by raising blood sugar through several mechanisms, including causing the liver to make more sugar and preventing fat cells from taking up sugar. Dr. Keith Roach, oregonlive, 28 Feb. 2022 LaVine said Saturday the treatment including draining fluid from his knee and receiving two injections — cortisone to reduce inflammation and platelet-rich plasma to accelerate healing in his tendons and ligaments. Julia Poe,, 19 Feb. 2022 After examination yesterday, the doctor injected my knee with cortisone, explaining this was the last alternative before a knee replacement. Dr. Keith Roach, oregonlive, 16 Feb. 2022 For Kevin Metz, his first infection was heralded in October 2020 by a burning sensation on his skin, followed later by a nagging cough, trouble breathing and sleeping, and other symptoms, requiring a cortisone inhaler. Salvador Rizzo, Anchorage Daily News, 25 Jan. 2022 To deal with eczema-like symptoms of redness and itching, a topical steroid like cortisone is best. Janae Mckenzie, Glamour, 3 Aug. 2021 Lillard took a cortisone shot and returned Dec. 12. oregonlive, 22 Jan. 2022 The Blazers returned home and Lillard returned to the lineup after taking a cortisone shot. oregonlive, 12 Jan. 2022 See More

These example sentences are selected automatically from various online news sources to reflect current usage of the word 'cortisone.' Views expressed in the examples do not represent the opinion of Merriam-Webster or its editors. Send us feedback.

First Known Use of cortisone

1949, in the meaning defined above

History and Etymology for cortisone

alteration of corticosterone

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The first known use of cortisone was in 1949

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Last Updated

18 Apr 2022

Cite this Entry

“Cortisone.” Dictionary, Merriam-Webster, Accessed 19 May. 2022.

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More Definitions for cortisone


cor·​ti·​sone | \ -ˌsōn, -ˌzōn How to pronounce cortisone (audio) \

Medical Definition of cortisone

: a glucocorticoid C21H28O5 that is produced naturally in small amounts by the adrenal cortex and is administered in the form of its synthetic acetate C23H30O6 especially as replacement therapy for deficient adrenocortical secretion and as an anti-inflammatory agent (as for rheumatoid arthritis) — compare 11-dehydrocorticosterone

More from Merriam-Webster on cortisone

Nglish: Translation of cortisone for Spanish Speakers Encyclopedia article about cortisone


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