cor·​ti·​sone | \ ˈkȯr-tə-ˌsōn How to pronounce cortisone (audio) , -ˌzōn \

Definition of cortisone

: a glucocorticoid C21H28O5 of the adrenal cortex used in synthetic form especially as an anti-inflammatory agent (as for rheumatoid arthritis)

Examples of cortisone in a Sentence

Recent Examples on the Web Sabathia received a cortisone shot two weeks ago and was left off the roster during the Yankees’ division series against Minnesota. Bob Klapisch, New York Times, "‘He’s Given Everything’: C.C. Sabathia’s Career Ends in Pain," 18 Oct. 2019 The band rushed her to urgent care for a cortisone shot. Travis Deshong, Washington Post, "For D.C. pop band Shaed, the rock-and-roll dream is all about family," 17 Oct. 2019 Former Western Kentucky University trainer Danny Cobble lost his job after coming into conflict with then-Hilltoppers coach Bobby Petrino, having recommended surgery for a player Petrino wanted to be treated with a cortisone injection. Tim Sullivan, The Courier-Journal, "Louisville pays ex-men's tennis coach rather than follow its Pitino playbook," 19 Aug. 2019 Dickerson’s future: Alex Dickerson returned to the Bay Area to have a cortisone shot in his right side. John Shea,, "Giants’ crowded bullpen keeps growing, more options for future," 7 Sep. 2019 The outfielder received a cortisone shot in his sore right oblique on Sunday. Kerry Crowley, The Mercury News, "San Francisco Giants fire eight pro scouts, brace for significant changes," 10 Sep. 2019 Merck & Company first produced cortisone commercially in 1948 or 1949 by a costly and complex process of chemical transformations. Robert D. Mcfadden, New York Times, "George Rosenkranz, a Developer of the Birth Control Pill, Dies at 102," 23 June 2019 Sabathia was making his first start off the IL in Sunday night’s 8-5 loss to the Red Sox, after having a cortisone and lubricant shot in his arthritic knee, which has no cartilage. Kristie Ackert,, "Second Dallas Keuchel bidding war begins today; Yankees need him more than most," 3 June 2019 Jerad Eickhoff had a cortisone shot Monday and the Phillies do not have a timetable for his return. Matt Breen,, "Phillies' Maikel Franco adjusting to life as a platoon player; Alec Bohm impresses Gabe Kapler," 12 June 2018

These example sentences are selected automatically from various online news sources to reflect current usage of the word 'cortisone.' Views expressed in the examples do not represent the opinion of Merriam-Webster or its editors. Send us feedback.

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First Known Use of cortisone

1949, in the meaning defined above

History and Etymology for cortisone

alteration of corticosterone

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Time Traveler for cortisone

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The first known use of cortisone was in 1949

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Last Updated

6 Dec 2019

Cite this Entry

“Cortisone.” The Dictionary, Merriam-Webster Inc., Accessed 6 December 2019.

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How to pronounce cortisone (audio)

English Language Learners Definition of cortisone

medical : a hormone that is used to treat arthritis and other diseases


cor·​ti·​sone | \ -ˌsōn, -ˌzōn How to pronounce cortisone (audio) \

Medical Definition of cortisone

: a glucocorticoid C21H28O5 that is produced naturally in small amounts by the adrenal cortex and is administered in the form of its synthetic acetate C23H30O6 especially as replacement therapy for deficient adrenocortical secretion and as an anti-inflammatory agent (as for rheumatoid arthritis) — compare 11-dehydrocorticosterone

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More from Merriam-Webster on cortisone

Rhyming Dictionary: Words that rhyme with cortisone

Spanish Central: Translation of cortisone

Nglish: Translation of cortisone for Spanish Speakers Encyclopedia article about cortisone

Comments on cortisone

What made you want to look up cortisone? Please tell us where you read or heard it (including the quote, if possible).


very cautious or careful

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