Guillain-Barré syndrome

noun Guil·lain-Bar·ré syndrome \ ˌgē-ˌlan-ˌbä-ˈrā- , ˌgē-yaⁿ- \

Definition of Guillain-Barré syndrome

: an uncommon autoimmune disorder of sudden onset that is an inflammatory neuropathy affecting the peripheral nervous system, that is initially marked by tingling, numbness, weakness, or loss of sensation in the feet and legs usually spreading to the arms, upper body, and face, that often causes severe nerve pain and breathing difficulties and sometimes progresses to paralysis and in rare instances death
Note: The cause of Guillain-Barré syndrome is unknown but individuals often experience onset a few weeks after a respiratory or gastrointestinal illness. Recovery from Guillain-Barré syndrome typically occurs within six to twelve months from initial onset but may take up to three years. Upon recovery, some individuals may have residual numbness, tingling, and weakness.

Origin and Etymology of guillain-barré syndrome

Georges Guillain †1961 French physician and Jean A. Barré †1967 French neurologist


Medical Dictionary

Guillain-Barré syndrome

noun Guil·lain-Bar·ré syndrome \ ˌgē-ˌlan-ˌbä-ˈrā- , ˌgē-yaⁿ- \

medical Definition of Guillain-Barré syndrome

: a polyneuritis of unknown cause characterized especially by muscle weakness and paralysis abbreviation GBS called also Landry's paralysis

Biographical Note for guillain-barré syndrome

  • Guillain play \gē-yaⁿ\, Georges Charles (1876–1961), and Barré play \bä-rā\, Jean Alexander (1880–1967), French neurologists. Guillain published several significant neurological studies concerning the brain and the spinal column. An authority on the spinal column in particular, he made studies of the cerebrospinal fluid and the marrow of the spinal cord. Guillain and Barré published their description of the Guillain-Barré syndrome in 1916.

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