Marfan syndrome

noun

Mar·​fan syndrome ˈmär-ˌfan- 

variants or Marfan's syndrome

ˈmär-ˌfanz- 

: a disorder of connective tissue that is inherited as a dominant trait and is characterized by abnormal elongation of the long bones and often by ocular and circulatory defects

Word History

Etymology

Antonin Bernard Jean Marfan †1942 French pediatrician

First Known Use

circa 1923, in the meaning defined above

Medical Definition

Marfan syndrome

noun

Mar·​fan syndrome ˈmär-ˌfan- 

variants or Marfan's syndrome

-ˌfanz- 

: a disorder of connective tissue that is inherited as a simple dominant trait, is caused by a defect in the gene controlling the production of fibrillin, and is characterized by abnormal elongation of the long bones and often by ocular and circulatory defects