genome

noun

ge·​nome ˈjē-ˌnōm How to pronounce genome (audio)
: one haploid set of chromosomes with the genes they contain
broadly : the genetic material of an organism compare proteome

Examples of genome in a Sentence

Recent Examples on the Web
Examples are automatically compiled from online sources to show current usage. Read More Opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback.
For instance, genome sequencers have been useful in developing personalized medicine. Mohammad Hosseini, Chicago Tribune, 4 June 2026 The team hopes to expand the model to additional cancer types and data sources, including international cancer genome datasets and other forms of clinical information, including imaging and electronic health records. Noah Lyons, San Diego Union-Tribune, 2 June 2026 And as for the peptide itself, genetic material that codes for its unique amino acid sequence hasn’t been found in the human genome or gut microbiome. Sara Talpos — Undark, STAT, 1 June 2026 Whole genome sequencing linked his illness to the outbreak strain associated with The Kebab Shop beef kofta, according to the lawsuit. Andrea Flores, Los Angeles Times, 31 May 2026 See All Example Sentences for genome

Word History

Etymology

German Genom, from Gen gene + -om (as in Chromosom chromosome)

First Known Use

1926, in the meaning defined above

Time Traveler
The first known use of genome was in 1926

Browse Nearby Words

Cite this Entry

“Genome.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/genome. Accessed 10 Jun. 2026.

Medical Definition

genome

noun
ge·​nome ˈjē-ˌnōm How to pronounce genome (audio)
: one haploid set of chromosomes with the genes they contain
broadly : the genetic material of an organism
The idea behind sequencing an organism's genome—decoding, letter by letter, the message contained in every last one of its genes—is that it would tell us a lot about how the organism works. Lori Oliwenstein, Discover

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