genome

noun

ge·​nome ˈjē-ˌnōm 

: one haploid set of chromosomes with the genes they contain

broadly : the genetic material of an organism compare proteome

Examples of genome in a Sentence

Recent Examples on the Web

Beethoven’s genome has been made publicly available, and a 2024 study revealed that the composer experienced lead poisoning, as well as elevated levels of arsenic and mercury. —Ashley Strickland, CNN Money, 12 Dec. 2025

However, new genome sequencing data reveals an unexpected twist to this long evolutionary story. —David Toews, The Conversation, 11 Dec. 2025

Czechoslovakian and Saarloos wolfdogs were found to have the highest levels of wolf ancestry, between 23 and 40% of their genomes. —Jay Kakade december 09, New Atlas, 9 Dec. 2025

Orchid’s approach involves whole genome sequencing, and expands on traditional screening by sequencing nearly all of an embryo’s genome. —Amanda Gerut, Fortune, 29 Nov. 2025

Word History

Etymology

German Genom, from Gen gene + -om (as in Chromosom chromosome)

First Known Use

1926, in the meaning defined above

Phrases Containing genome

• genome editing

Rhymes for genome

• biome
• megohm
• nichrome
• noisome
• prodrome
• radome
• rhizome
• shalom
• syndrome
• acrosome
• aerodrome
• catacomb

Medical Definition

genome

noun

ge·​nome ˈjē-ˌnōm 

: one haploid set of chromosomes with the genes they contain

broadly : the genetic material of an organism

The idea behind sequencing an organism's genome—decoding, letter by letter, the message contained in every last one of its genes—is that it would tell us a lot about how the organism works.

—Lori Oliwenstein, Discover