pro·​te·​ome | \ ˈprō-tē-ˌōm How to pronounce proteome (audio) \

Definition of proteome

: the complement of proteins expressed in a cell, tissue, or organism by a genome

Examples of proteome in a Sentence

Recent Examples on the Web Their effort centers on building a proteome — the complete collection of proteins that LECA was probably capable of making. Quanta Magazine, "Researchers Rethink the Ancestry of Complex Cells," 9 Apr. 2019 Moses’ lab, which receives support from the NIH, foundations, and philanthropic organizations, looks at how cancer affects an individual’s protein profile, or proteome, and compares the presence of these proteins in urine samples., "1. SEARCHING FOR AN ALZHEIMER’S SOURCE," 27 Sep. 2019 In 2012, Keith Dunker of Indiana University and his colleagues looked for these telltale stretches of amino acids in databases of eukaryotic and prokaryotic proteomes. Quanta Magazine, "How Viruses May Have Led to Complex Life," 24 Jan. 2017 Instead of identifying them one protein at a time, as has classically been done, Cravatt develops rules that apply to wide swathes of the universe of proteins, or the proteome. Bradley J. Fikes,, "Scripps' Ben Cravatt elected to National Academy of Medicine," 16 Oct. 2017

These example sentences are selected automatically from various online news sources to reflect current usage of the word 'proteome.' Views expressed in the examples do not represent the opinion of Merriam-Webster or its editors. Send us feedback.

See More

First Known Use of proteome

1995, in the meaning defined above

History and Etymology for proteome

prote- + -ome (as in genome)

Keep scrolling for more

Learn More about proteome

Time Traveler for proteome

Time Traveler

The first known use of proteome was in 1995

See more words from the same year

Statistics for proteome

Cite this Entry

“Proteome.” Dictionary, Merriam-Webster, Accessed 21 Jan. 2021.

Keep scrolling for more

More Definitions for proteome


pro·​te·​ome | \ ˈprōt-ē-ˌōm How to pronounce proteome (audio) \

Medical Definition of proteome

: the complement of proteins expressed in a cell, tissue, or organism by a genome

Comments on proteome

What made you want to look up proteome? Please tell us where you read or heard it (including the quote, if possible).


Test Your Vocabulary

Words of Snow and Ice Quiz

  • image1037863653
  • Which of the following refers to thin, bending ice, or to the act of running over such ice?
True or False

Test your knowledge - and maybe learn something along the way.


Anagram puzzles meet word search.

Love words? Need even more definitions?

Subscribe to America's largest dictionary and get thousands more definitions and advanced search—ad free!