Down syndrome

noun

variants: or Down's syndrome

Definition of Down syndrome

: a congenital condition characterized especially by developmental delays, usually mild to moderate impairment in cognitive functioning, short stature, upward slanting eyes, a flattened nasal bridge, broad hands with short fingers, decreased muscle tone, and by trisomy of the human chromosome numbered 21

— called also trisomy 21

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The first known use of Down syndrome was in 1961

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More Definitions for Down syndrome

Down syndrome

noun

English Language Learners Definition of Down syndrome

medical : a condition that someone is born with and that causes below average mental abilities and problems in physical development

See the full definition for Down syndrome in the English Language Learners Dictionary

Down syndrome

noun

variants: or Down's syndrome

Medical Definition of Down syndrome

: a congenital condition characterized especially by mental retardation, short stature, relatively small head, upward slanting eyes usually with epicanthal folds, flattened nasal bridge, broad hands with short fingers, decreased muscle tone, and by trisomy of the human chromosome numbered 21

— called also Down, Down's, trisomy 21