infirmity

contagion, contagious disease

contagium, infection

attack, bout, fit, spell

debility, decrepitude, feebleness, frailness, lameness, sickliness, unhealthiness, unsoundness, unwellness, weakness

malaise, matter, pip

epidemic, pest, pestilence, plague

decay, decrepitude

breakdown, collapse, prostration

exhaustion, fatigue, lassitude, weariness

defenselessness, helplessness, impotence, impuissance, powerlessness

effeteness, softness, tenderness

disablement, incapacitation, invalidism

damage, harm, hurt, impairment, injury