aching

agonizing, excruciating, torturous

damaging, deleterious, detrimental, harmful, hurtful, injurious, noxious, pernicious

raw, tender

bleeding, burning, chafing, cramping, festering

itching, nagging, pinching, pricking, prickling, smarting, stinging

inflamed (also enflamed), swollen

grievous, severe, threatening, wounding

elegiac (also elegiacal), melancholy

dejected, depressed, despondent, disconsolate, dispirited, downcast, downhearted, heartsick, heartsore, inconsolable, tearful

brokenhearted, careworn, crestfallen, downcast, downhearted, forlorn, gloomy, glum, low-spirited, miserable, sad, triste, unhappy, woebegone

bawling, crying, groaning, howling, keening, moaning, yammering

black, bleak, cheerless, comfortless, dark, darkening, desolate, dismal, dreary, funereal, gloomy, glum, gray (also grey), joyless, low, miserable, moody, morbid, morose, pathetic, pessimistic, piteous, saturnine, somber (or sombre), sullen