Synonyms of deleterious

deleterious

adjective

ˌde-lə-ˈtir-ē-əs 

as in harmful

causing or capable of causing harm

nicotine has long been recognized as a deleterious substance

Synonyms & Similar Words

• harmful
• detrimental
• adverse
• damaging
• dangerous
• bad
• injurious
• hazardous
• pernicious
• poisonous
• baneful
• infectious
• prejudicial
• noxious
• evil
• hurtful
• baleful
• mischievous
• wicked
• ill
• nocuous
• destructive
• hostile
• deadly
• lethal
• unsafe
• infective
• inimical
• venomous
• sinister
• insidious
• risky
• unfriendly
• threatening
• ominous
• fatal
• contagious
• perilous
• menacing
• malignant
• unhealthful
• pestiferous
• pestilential
• unhealthy
• unwholesome
• ruinous
• unsound
• pestilent
• killer
• parlous
• nasty
• imperiling
• jeopardizing
• noisome

Antonyms & Near Antonyms

• beneficial
• benign
• harmless
• innocuous
• safe
• useful
• innocent
• advantageous
• favorable
• inoffensive
• good
• propitious
• salutary
• healthful
• healthy
• helpful
• anodyne
• wholesome
• remedial
• curative
• salubrious
• palliative
• sound
• hurtless
• secure
• benignant
• nontoxic
• noninfectious
• nonlethal
• nondestructive
• noncorrosive
• nonpoisonous
• nonfatal
• nonpolluting
• nonvenomous

Synonym Chooser

How is the word deleterious different from other adjectives like it?

Some common synonyms of deleterious are baneful, detrimental, noxious, and pernicious. While all these words mean "exceedingly harmful," deleterious applies to what has an often unsuspected harmful effect.

a diet found to have deleterious effects

When is baneful a more appropriate choice than deleterious?

The synonyms baneful and deleterious are sometimes interchangeable, but baneful implies injury through poisoning or destroying.

the baneful notion that discipline destroys creativity

When would detrimental be a good substitute for deleterious?

The words detrimental and deleterious are synonyms, but do differ in nuance. Specifically, detrimental implies obvious harmfulness to something specified.

the detrimental effects of excessive drinking

When can noxious be used instead of deleterious?

The meanings of noxious and deleterious largely overlap; however, noxious applies to what is both offensive and injurious to the health of a body or mind.

noxious chemical fumes

Where would pernicious be a reasonable alternative to deleterious?

The words pernicious and deleterious can be used in similar contexts, but pernicious implies irreparable harm done through evil or insidious corrupting or undermining.

the claim that pornography has a pernicious effect on society

Example Sentences

Recent Examples of deleterious

The quickest way to artificially boost a company’s stock price is to slash R&D, gut capex, and initiate massive share buybacks, often with deleterious long-term consequences. — Jeffrey Sonnenfeld, Fortune, 6 July 2026

Lawyers have been accused of unnecessary complexity, deleterious delay, excessive cost, and self-interest for centuries. — Joseph Andrew, Forbes.com, 2 July 2026

The primary question is whether this crowded field of new entrants is actually accomplishing anything, or whether its members are simply tripping over one another with deleterious impact. — Jeffrey Sonnenfeld, Time, 28 June 2026

France is a climate-conscious population; there has been a strong aversion to air-conditioning, understood, rightly, as a Band-Aid that might hasten the deleterious resolution of the climate crisis. — Doreen St. Félix, New Yorker, 27 June 2026

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