defile

1 to make unfit for use by the addition of something harmful or undesirable supplies of meat that had been defiled by maggots Synonyms befoul, contaminate, foul, poison, pollute, taintRelated Words infect; begrime, besmirch, blacken, dirty, foul up, grime, mire, muddy, smirch, smudge, soil, stain, sully; corrupt, rot, spoil; adulterate, doctor; dilute, water downNear Antonyms clarify, clean, cleanse, clear, distill (also distil), purge; filter; disinfect, sanitize, sterilizeAntonyms decontaminate, purify

2 to treat (a sacred place or object) shamefully or with great disrespect art conservators were careful not to do anything that might defile the holy relic Synonyms desecrate, profane, violateRelated Words deconsecrate, desacralize, desanctify; blaspheme, curse, swear; befoul, contaminate, foul, poison, pollute, soil, sully, taint; affront, defame, insult, offend, outrage; annihilate, crush, decimate, demolish, desolate, destroy, devastate, ravage, raze, ruin, waste, wreck; despoil, loot, pillage, plunder, raid, ransack, rob, sack, spoil, stripNear Antonyms bless, consecrate, dedicate, hallow, sanctify; honor, respect; cleanse, purge, purify