1
                    as in significant
                                                
              
          
                                                      sufficiently large in size, amount, or number to merit attention                                       
              
                             with several blockbuster hits under her belt, the actress now commands some major cash for appearing in a movie                         
                
                                                                                                                                                                                                                    
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2
                    as in important
                                                
              
          
                                                      having great meaning or lasting effect                                       
              
                             a major change in how science is taught in our high schools                         
                
                                                                                                                                                                                                                    
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  Merriam-Webster unabridged




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