operate

1 to control the mechanical operation of do not operate heavy machinery, including cars, after taking this medication Synonyms handle, run, work Related Words use; maneuver, manipulate, ply, wield; command, control, direct, drive, guide, pilot, steer

2 to look after and make decisions about it takes years to learn how to operate that kind of business so that it makes money Synonyms administer, administrate, carry on, control, direct, govern, guide, handle, keep, manage, conduct, overlook, oversee, preside (over), regulate, run, steward, superintend, supervise, tendRelated Words care (for), mind, watch; lead, pilot, steer; guard, protect, safeguard; micromanage, stage-manage; codirect, comanage

3 to produce a desired effect the medicine will take an hour or so to operate the first time you use it Synonyms act, perform, take, workRelated Words behave, react, respond; affect, influence, sway; pan out, redound, resultNear Antonyms backfire; fizzle

4 to put into action or service wouldn't dream of operating a vehicle under the influence of alcohol Synonyms apply, employ, exercise, exploit, harness, use, utilizeRelated Words handle, manipulate, wield; direct, run, work; cannibalize, recycle, reuseNear Antonyms ignore, neglect; misapply, misuse