as in sedative
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Recent Examples of depressant
At the time of the 1998 murder-suicide, Brynn had cocaine, alcohol and a prescription anti-depressant in her system, The New York Times reported.
—
Emily Blackwood, PEOPLE, 17 Apr. 2026
The drink is known for its mild euphoria and depressant effects.
—Kristen Rogers, CNN Money, 26 Aug. 2025
See All Example Sentences for depressant
Emily Blackwood, PEOPLE, 17 Apr. 2026
The drink is known for its mild euphoria and depressant effects.
—Kristen Rogers, CNN Money, 26 Aug. 2025
See All Example Sentences for depressant
Recent Examples of Synonyms for depressant
Adjective
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In that sense, pregabalin (brand name Lyrica), which is used to treat nerve pain and is associated with sedative effects, is less common.—
Erin Vanderhoof,
Vanity Fair,
29 Apr. 2026
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The result is a calmer, quieter brain at bedtime without any sedative effect.—
Allison Palmer,
Sacbee.com,
23 Apr. 2026
Adjective
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Ashwagandha comes with natural relaxant properties to calm down your mind and recharge your brain.—
Discover Magazine,
Discover Magazine,
29 Apr. 2023
Adjective
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Hydrocodone is an opiate used in drugs like Vicodin.—
Jason P. Frank,
Vulture,
31 Mar. 2026
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Naloxone, the active drug in Narcan, is only effective on opioids and not on stimulants like cocaine, which would suggest the substance Dick used was adulterated with an opiate such as fentanyl.—
Jessica Schladebeck,
New York Daily News,
4 Mar. 2026
Adjective
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The suspect, identified as 32-year-old Keith Johnson, was arrested and booked on suspicion of felony vandalism, felony burglary, possession of narcotic paraphernalia, possession of another person's identifying information and probation violation.—
Tim Fang,
CBS News,
28 Apr. 2026
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Although the trial may have gone in Scott's favor, Gill was highly critical of the Middletown narcotic detective's actions and questioned his motivation.—
Juliet Pennington,
PEOPLE,
24 Apr. 2026
Adjective
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The London Symphony Orchestra and the Escolania de Montserrat i Cor Cambra Palau de la Música Catalana choir bolster the album, their arrangements ranging from anxious and erratic to soothing and hypnotic.—
Larisha Paul,
Rolling Stone,
2 May 2026
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This reimagining of a niche Japanese Dreamcast game turns the simple game of squash into a mind-bending journey through space and time, thanks to hypnotic visuals and music.—
George Yang,
PC Magazine,
1 May 2026
Adjective
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These are not actions of two people who can’t wait to rip their clothes off, which is what this movie needed to make its central pairing less soporific.—
Roxana Hadadi,
Vulture,
14 Mar. 2026
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Whereas the Greek hero knew to avoid the Lotus-Eaters’ soporific drug, Rip drinks deeply of the enchanted Dutch liquor.—
John Swansburg,
The Atlantic,
10 Oct. 2025
Cite this Entry
“Depressant.” Merriam-Webster.com Thesaurus, Merriam-Webster, https://www.merriam-webster.com/thesaurus/depressant. Accessed 5 May. 2026.
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