as in sedative
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Recent Examples of depressant
At the time of the 1998 murder-suicide, Brynn had cocaine, alcohol and a prescription anti-depressant in her system, The New York Times reported.
—
Emily Blackwood, PEOPLE, 17 Apr. 2026
The drink is known for its mild euphoria and depressant effects.
—Kristen Rogers, CNN Money, 26 Aug. 2025
See All Example Sentences for depressant
Emily Blackwood, PEOPLE, 17 Apr. 2026
The drink is known for its mild euphoria and depressant effects.
—Kristen Rogers, CNN Money, 26 Aug. 2025
See All Example Sentences for depressant
Recent Examples of Synonyms for depressant
Adjective
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Chamomile tea contains apigenin, which binds to GABA receptors producing a mild sedative effect.—
Allison Palmer,
Fort Worth Star-Telegram,
15 Apr. 2026
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Prescription medicines used to treat anxiety, including benzodiazepines, are also flagged due to their sedative effects.—
Amanda Greenwood,
MSNBC Newsweek,
1 Apr. 2026
Adjective
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Ashwagandha comes with natural relaxant properties to calm down your mind and recharge your brain.—
Discover Magazine,
Discover Magazine,
29 Apr. 2023
Adjective
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Hydrocodone is an opiate used in drugs like Vicodin.—
Jason P. Frank,
Vulture,
31 Mar. 2026
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Naloxone, the active drug in Narcan, is only effective on opioids and not on stimulants like cocaine, which would suggest the substance Dick used was adulterated with an opiate such as fentanyl.—
Jessica Schladebeck,
New York Daily News,
4 Mar. 2026
Adjective
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Billy [William Friedkin, the director] out on narcotic raids.—
Richard Brody,
New Yorker,
6 Apr. 2026
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Last week, Acuna was charged with possession of cocaine and possession of narcotic drugs.—
Louis Casiano,
FOXNews.com,
6 Apr. 2026
Adjective
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That smell of Sumatra — earthy, smoky, almost hypnotic.—
Nick El Hajj,
USA Today,
15 Apr. 2026
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There’s a huge connection between the hypnotic energy of your music and your live PORTAL shows.—
Danny Klein,
SPIN,
13 Apr. 2026
Adjective
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These are not actions of two people who can’t wait to rip their clothes off, which is what this movie needed to make its central pairing less soporific.—
Roxana Hadadi,
Vulture,
14 Mar. 2026
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Whereas the Greek hero knew to avoid the Lotus-Eaters’ soporific drug, Rip drinks deeply of the enchanted Dutch liquor.—
John Swansburg,
The Atlantic,
10 Oct. 2025
Cite this Entry
“Depressant.” Merriam-Webster.com Thesaurus, Merriam-Webster, https://www.merriam-webster.com/thesaurus/depressant. Accessed 21 Apr. 2026.
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