de·​pres·​sant | \ di-ˈpre-sᵊnt How to pronounce depressant (audio) , dē- \

Definition of depressant

: one that depresses specifically : an agent that reduces a bodily functional activity or an instinctive desire (such as appetite)

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Other Words from depressant

depressant adjective

Examples of depressant in a Sentence

Recent Examples on the Web Also caution is warranted when taken in combination with alcohol or other central nervous system depressants. Blair Chance, ABC News, "New migraine medication given the green light," 15 Feb. 2020 The most common ones are anti-depressants and anti-anxiety medications. Vanessa Marin, Allure, "Ask a Sex Therapist: My Boyfriend Doesn't Orgasm When We Have Vaginal Intercourse," 6 Feb. 2020 Kamille’s remains tested positive for methamphetamine and Trazodone, an anti-depressant used to treat insomnia, according to testimony. Carol Robinson |, al, "These tragic crimes horrified Alabama in 2019," 30 Dec. 2019 Stallworth also had a prescription for Trazadone, an anti-depressant used to treat insomnia, that was found in McKinney’s system, according to the outlet. Jeff Truesdell,, "Meth and Sedatives Found in Body of Abducted Ala. 3-Year-Old Kamille ‘Cupcake’ McKinney: Testimony," 11 Dec. 2019 Trazodone, an anti-depressant sometimes used as a sedative. Carol Robinson |, al, "Kamille ‘Cupcake’ McKinney suspect said she saw child’s sexual assault," 13 Dec. 2019 In 2009, he was briefly hospitalized after being attacked by his pet Maltese poodle, Sumo; the dog was said to be taking anti-depressants because of its unpredictability. Keith Richburg, Washington Post, "Jacques Chirac, flamboyant French president who opposed U.S. invasion of Iraq, dies at 86," 26 Sep. 2019 The spike in meth use coincides with an existing opiate crisis, and many people have turned to using both the depressant and stimulant. oregonlive, "Homeless with HIV: A lack of housing makes a preventable disease deadly in Oregon," 10 Nov. 2019 Examples included antibiotics, anti-inflammatory (ibuprofen), anti-depressants, anti-diabetics, stimulants (caffeine), and reproductive and thyroid hormones. David Taylor, Houston Chronicle, "Cleveland PD offering safe place to dispose of drugs," 13 Sep. 2019

These example sentences are selected automatically from various online news sources to reflect current usage of the word 'depressant.' Views expressed in the examples do not represent the opinion of Merriam-Webster or its editors. Send us feedback.

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First Known Use of depressant

1876, in the meaning defined above

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Time Traveler for depressant

Time Traveler

The first known use of depressant was in 1876

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Statistics for depressant

Cite this Entry

“Depressant.” Dictionary, Merriam-Webster, Accessed 26 May. 2020.

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More Definitions for depressant


How to pronounce depressant (audio)

English Language Learners Definition of depressant

: a chemical substance (such as a drug) that makes a body's systems less active


de·​pres·​sant | \ di-ˈpre-sᵊnt How to pronounce depressant (audio) \

Kids Definition of depressant

: a drug that slows the activity of the nervous system


de·​pres·​sant | \ -ᵊnt How to pronounce depressant (audio) \

Medical Definition of depressant

 (Entry 1 of 2)

: tending to depress especially : lowering or tending to lower functional or vital activity a drug with a depressant effect on heart rate



Medical Definition of depressant (Entry 2 of 2)

: one that depresses specifically : an agent that reduces bodily functional activity or an instinctive desire (as appetite) a depressant of intestinal spasm

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