gene

noun

ˈjēn 

plural genes

: a specific sequence of nucleotides in DNA or RNA that is located usually on a chromosome and that is the functional unit of inheritance controlling the transmission and expression of one or more traits by specifying the structure of a particular polypeptide and especially a protein or controlling the function of other genetic material

Examples of gene in a Sentence

She inherited a good set of genes from her parents.

Recent Examples on the Web

Eli Lilly is also studying an oral drug called muvalaplin, and CRISPR gene-editing technology designed to permanently switch off the gene that produces Lp(a) is in early development. — Erika Edwards, NBC news, 7 Nov. 2026

Fetal gene editing would be less invasive than that, Peranteau said. — Gerry Smith, CNBC, 6 Nov. 2026

Located on the X chromosome, ZFX belongs to a small group of genes that escape a process known as X chromosome inactivation. — Daniella Gray, MSNBC Newsweek, 6 Nov. 2026

This higher baseline expression in female brains could therefore help maintain activity across this network when other genes are disrupted. — New Atlas, 5 Nov. 2026

Word History

Etymology

German Gen, short for Pangen, from pan- + -gen

First Known Use

1909, in the meaning defined above

Phrases Containing gene

• gene conversion
• gene editing
• gene flow
• gene frequency
• gene mutation
• gene pool
• gene-splicing
• gene therapy
• lethal gene
• regulator gene
• regulatory gene
• structural gene
• tumor suppressor gene

Rhymes for gene

• bean
• bein
• bien
• bouin
• clean
• deen
• acetylcysteine
• antisubmarine
• dichlorobenzene
• dimethylamine
• diphenylamine
• ethanolamine

Kids Definition

gene

noun

ˈjēn 

: a part of DNA or sometimes RNA that is usually located on a chromosome and that contains chemical information needed to make a particular protein (as an enzyme) controlling or influencing an inherited bodily trait or activity (as eye color or metabolism) or that influences or controls the activity of another gene or genes

Medical Definition

gene

noun

ˈjēn 

: a specific sequence of nucleotides in DNA or RNA that is located usually on a chromosome and that is the functional unit of inheritance controlling the transmission and expression of one or more traits by specifying the structure of a particular polypeptide and especially a protein or controlling the function of other genetic material

called also determinant, determiner, factor