gene mutation

noun
plural gene mutations

Definition of gene mutation

: a permanent alteration (as by point mutation or frameshift mutation) in the nucleotide sequence of a gene Researchers have identified a gene mutation that's believed to predispose people to malignant melanoma, the deadliest and most aggressive type of skin cancer.Health News — compare point mutation

Examples of gene mutation in a Sentence

Recent Examples on the Web But the presence of a gene mutation could play a considerable role in the cause of Parkinson's—and there's an enormous push to advance research on genetics in order to better understand the disease, improve treatment and, hopefully, discover a cure. Patti Greco, Health.com, 22 Sep. 2021 Within a matter of days, the test came back positive for the CHEK2 gene mutation, a mutation that is associated with breast cancer but has not yet been heavily researched. Jessica Zucker, Condé Nast Traveler, 1 Oct. 2021 Individuals who are of Ashkenazi Jewish and North African Berber descent are particularly prone to this gene mutation. Patti Greco, Health.com, 22 Sep. 2021 Once the biotech determined the study data showed the drug is safe and effective, the program would be opened to a broader group of patients with the gene mutation in the fall. Ed Silverman Reprints, STAT, 22 Aug. 2021 Just before the launch, the sisters got tested for the BRCA2 gene mutation. Geri Stengel, Forbes, 8 Sep. 2021 In the early nineties, research on C. elegans, a tiny nematode worm that resembles a fleck of lint, showed that a single gene mutation extended its life, and that another mutation blocked that extension. Margaret Talbot, The New Yorker, 11 Aug. 2021 Once the biotech determined the study data showed the drug is safe and effective, the program would be opened to a broader group of patients with the gene mutation in the fall. Ed Silverman Reprints, STAT, 22 Aug. 2021 But Seattle Cancer Care Alliance, a partner of Fred Hutchinson Cancer Research Center, where Marsh’s mother had been an oncology nurse, did know about the gene mutation. BostonGlobe.com, 22 Aug. 2021

These example sentences are selected automatically from various online news sources to reflect current usage of the word 'gene mutation.' Views expressed in the examples do not represent the opinion of Merriam-Webster or its editors. Send us feedback.

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First Known Use of gene mutation

1904, in the meaning defined above

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Time Traveler for gene mutation

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The first known use of gene mutation was in 1904

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Dictionary Entries Near gene mutation

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gene mutation

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Last Updated

23 Oct 2021

Cite this Entry

“Gene mutation.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/gene%20mutation. Accessed 24 Oct. 2021.

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More Definitions for gene mutation

gene mutation

noun

Medical Definition of gene mutation

: a permanent alteration (as a point mutation or frameshift mutation) in the nucleotide sequence of a gene … there is a 50 percent chance each offspring will inherit the gene mutation and may develop the disease.— Fred Cicetti In early August the team published a study in Nature that chronicled how a single gene mutation in a laboratory strain of Escherichia coli could create a bacterium resistant to triclosan …— Gary Stix

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