gene mutation


Definition of gene mutation 

: mutation due to fundamental intramolecular reorganization of a gene — compare point mutation

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These cases are sometimes due to three specific gene mutations or other genetic factors. Korin Miller, SELF, "10 Facts About Alzheimer's Disease You Should Know," 28 Sep. 2018 According to research from the American Chemical Society's national meeting, out of 109 lice samples collected over 30 states, 104 had high levels of gene mutations. Good Housekeeping, "Yikes! Super-Strains of Lice Have Spread to 25 States," 26 Feb. 2016 Over the past two decades Casanova, often working with Laurent Abel of Necker Hospital for Sick Children in Paris, and a few other laboratories have identified dozens of single-gene mutations causing this kind of vulnerability. Claudia Wallis, Scientific American, "Extreme Flu? Weird Encephalitis? It May Be Your Genes," 13 July 2018 The Food and Drug Administration not long ago announced its authorization that permits genetics testing company 23andMe to market a test for gene mutations associated with risk of breast and ovarian cancer. Katherine Drabiak, Washington Post, "As more women turn to genetic testing for breast cancer, understanding risk is key," 25 June 2018 What finally caused Facebook to close the loophole were complaints from a group of women with the BRCA gene, a gene mutation associated with an elevated risk of breast cancer. Brittany Shoot, Fortune, "Facebook Closes Loophole That Revealed Personal Data of People in 'Closed' Groups," 12 July 2018 About 80% of patients have a specific gene mutation associated with Dravet, but Maya didn’t. Adam Adache, Time, "My 10-Year-Old Daughter Takes the First FDA-Approved Marijuana Drug. It's Changed Our Lives," 26 June 2018 Science has shown that the BRCA1 and BRCA2 gene mutations, if inherited, can significantly increase a woman’s risk of developing breast or ovarian cancer in her lifetime. Paul Sisson,, "Free panel to explore living with inherited cancer risk," 10 July 2018 Javahery said Kalea and Noah's tumors, which measured 3.5 cm and 5 cm, respectively, are being tested for gene mutations to help determine what may have caused them. Lindsey Bever, Washington Post, "A 6-year-old was diagnosed with an aggressive brain tumor. Then her little brother was, too.," 7 July 2018

These example sentences are selected automatically from various online news sources to reflect current usage of the word 'gene mutation.' Views expressed in the examples do not represent the opinion of Merriam-Webster or its editors. Send us feedback.

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First Known Use of gene mutation

1921, in the meaning defined above

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Last Updated

12 Nov 2018

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The first known use of gene mutation was in 1921

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gene mutation


Medical Definition of gene mutation 

: mutation due to fundamental intramolecular reorganization of a gene — see point mutation

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