Merriam-Webster Logo
SINCE 1828
Menu
×

An Encyclopædia Britannica Company

See What's Trending Now See More Trending Words

frameshift

play
adjective frame·shift \ ˈfrām-ˌshift \

Definition of frameshift

:relating to, being, or causing a mutation in which a number of nucleotides not divisible by three is inserted or deleted so as to change the reading frame of some triplet codons during genetic translation
—

frameshift

noun

People Are Reading

alt-59c2960017c94
The Ambiguity of Pushing 'Up' and 'Back'
alt-59c2cb9e9ef54
Trending: Ivanka: "An 'Otherwise' Incredible Day"
young-plant-shoots
Merriam-Webster's New Words Quiz—Fall 2017 Edition!
video-title-words-of-the-year-1066
Words of the Year: 1066

First Known Use of frameshift

1965

Medical Dictionary

frameshift

play
adjective frame·shift \ -ˌshift \

medical Definition of frameshift

:relating to, being, or causing a mutation in which a number of nucleotides not divisible by three is inserted or deleted so that some triplet codons are read incorrectly during genetic translation
  • frameshift mutations
  • frameshift mutagens
—

frameshift

noun

Learn More about frameshift

  1. See words that rhyme with frameshift

Seen and Heard

What made you want to look up frameshift? Please tell us where you read or heard it (including the quote, if possible).

show hide

Love words? Need even more definitions?

Subscribe to America's largest dictionary and get thousands more definitions and advanced search—ad free!

WORD OF THE DAY

shofar

play

a ram's-horn trumpet used in Judaism

Get Word of the Day daily email!

TRENDING NOW

  1. otherwise "in other respects"

  2. federalism Graham says bill gives power to states

  3. bodega "Don’t mess with the beloved bodega."

  4. carceral Of, relating to, or suggesting a jail or prison

  5. allegory No spoilers!

SEE ALL

BROWSE DICTIONARY

frameshift

Test Your Vocabulary

Merriam-Webster's New Words Quiz—Fall 2017 Edition!

  • young-plant-shoots
  • Which of the following is a new sense of the word bunny?
True or False

Test your knowledge - and maybe learn something along the way.

TAKE THE QUIZ
Bee Cubed

Test Your Knowledge - and learn some interesting things along the way.

TAKE THE QUIZ

Love words? Need even more definitions?

Subscribe to America's largest dictionary and get thousands more definitions and advanced search—ad free!

Words at Play

alt-59c2960017c94
The Ambiguity of Pushing 'Up' and 'Back'

When you push a meeting, where does it go?

image536372841
Silent Letters

When each letter can be seen but not heard

alt-59c17b8172892
'So Long': A Common But Mysterious Goodbye

Its origins are surprisingly murky.

alt-59c13729150dc
"Immune to" or "Immune from"?

Nobody is immune to this question.

Ask the Editors

video-title-words-of-the-year-1066
Words of the Year: 1066

Or, Why Pig Meat is Called 'Pork' and Cow Meat is Called 'Beef'

payday
How Often Is 'Biweekly'?

Don't get us started on 'bimonthly'

video-irregardless-grammar-peeve-blend-of-the-synonyms-irrespective-and-regardless
Irregardless

It is in fact a real word (but that doesn't mean you should use it).

video-moose-goose-weird-plurals
Weird Plurals

One goose, two geese. One moose, two... moose. What's up with that?

Word Games

young-plant-shoots
Merriam-Webster's New Words Quiz—Fall 2017 Edition!

You're going to have to memorize the dictionary again.

Take the quiz
stylized-drawing-of-woman-pole-vaulting-across-gap-to-get-trophy
Challenging Vocabulary Quiz Returns!

No tricks, just difficult words.

Take the quiz
True or False
True or False?

Test your knowledge - and maybe learn something along the way.

Take the quiz
Bee Cubed
Bee Cubed

Listen to the words and spell through all three levels.

Play the game