Merriam-Webster Logo
SINCE 1828
Menu
×

An Encyclopædia Britannica Company

frameshift

adjective frame·shift \ ˈfrām-ˌshift \
See What's Trending Now See More Trending Words

Definition of frameshift

: relating to, being, or causing a mutation in which a number of nucleotides not divisible by three is inserted or deleted so as to change the reading frame of some triplet codons during genetic translation
—

frameshift

noun

First Known Use of frameshift

1965

in the meaning defined above

See Words from the same year
NEW! Time Traveler

Medical Dictionary

frameshift

adjective frame·shift \ -ˌshift \

medical Definition of frameshift

: relating to, being, or causing a mutation in which a number of nucleotides not divisible by three is inserted or deleted so that some triplet codons are read incorrectly during genetic translation
  • frameshift mutations
  • frameshift mutagens
—

frameshift

noun

Learn More about frameshift

  1. See words that rhyme with frameshift

Seen and Heard

What made you want to look up frameshift? Please tell us where you read or heard it (including the quote, if possible).

show hide

Love words? Need even more definitions?

Subscribe to America's largest dictionary and get thousands more definitions and advanced search—ad free!

WORD OF THE DAY

loath

play

unwilling or reluctant

Get Word of the Day daily email!

TRENDING NOW

  1. symbiote 'an organism living in symbiosis'

  2. charlatan 'faker or fraud'

  3. lowlife 'a person of low moral character'

  4. kakistocracy 'government by the worst people'

  5. slimeball 'a morally repulsive or odious person'

SEE ALL

BROWSE DICTIONARY

frameshift

Test Your Vocabulary

Odd Habits and Quirks Quiz

  • image1926873504
  • Which of the following best describes an easily irritated person?
Name That Thing

Test your visual vocabulary with our 10-question challenge!

TAKE THE QUIZ
Bee Cubed

Test Your Knowledge - and learn some interesting things along the way.

TAKE THE QUIZ

Love words? Need even more definitions?

Subscribe to America's largest dictionary and get thousands more definitions and advanced search—ad free!

Words at Play

alt-5adf5d017e6bf
‘Sleight’ or ‘Slight’ of Hand?

Watch closely and be amazed.

alt-5ade0f1ca7a0c
'Complement' vs. 'Compliment'

The distinction is clear (now).

image236659401
Words from Letters in the Greek Alphabet

When English borrows from another alphabet

alt-5ada140ed3e28
'Preventive' or 'Preventative'?

Why not both?

Ask the Editors

image1760257654
2017 Word of the Year: Behind the Scenes

How we chose 'feminism'

video-title-words-of-the-year-1066
Words of the Year: 1066

Or, Why Pig Meat is Called 'Pork' and Cow Meat is Called 'Beef'

video-literally
Literally

How to use a word that (literally) drives some people nuts.

video-his-or-her
Is Singular 'They' a Better Choice?

The awkward case of 'his or her'

Word Games

image1926873504
Odd Habits and Quirks Quiz

Test your knowledge of strange human behaviors.

Take the quiz
cats-on-impossible-timber
More Confusing Words—Quiz

How many of these commonly confused words do you know?

Take the quiz
Name That Thing
Name That Thing

Test your visual vocabulary with our 10-question challenge!

Take the quiz
Bee Cubed
Bee Cubed

Listen to the words and spell through all three levels.

Play the game