: any of various nucleic acids that are usually the molecular basis of heredity, are constructed of a double helix held together by hydrogen bonds between purine and pyrimidine bases (see base entry 1 sense 6b) which project inward from two chains containing alternate links of deoxyribose and phosphate, and that in eukaryotes are localized chiefly in cell nuclei compare recombinant dna

Illustration of DNA

Illustration of dna
  • A molecular model
  • 1 hydrogen
  • 2 oxygen
  • 3 carbon in the helical phosphate ester chains
  • 4 carbon and nitrogen in the cross-linked purine and pyrimidine bases
  • 5 phosphorus
  • B double helix

Examples of DNA in a Sentence

Recent Examples on the Web
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Each time a cell divides, its DNA is copied, but mistakes inevitably creep in. Jerome Groopman, New Yorker, 6 Apr. 2026 It's embedded in Atlanta's cultural DNA, from Southern hip-hop to film, fashion, and Black American traditions. Zachary Bynum, CBS News, 5 Apr. 2026 Multiple attempts were made for a DNA comparison using semen found in Teresa’s underwear. Orlando Sentinel Editorial Board, Sun Sentinel, 4 Apr. 2026 Because ghost wolves have DNA from red wolves — a species once believed to be extinct and now existing only through captive breeding recovery programs — some researchers say preserving the hybrid coyote-wolf and its DNA could help bring back red wolves to their historic range. Ashley Soebroto, Houston Chronicle, 4 Apr. 2026 See All Example Sentences for DNA

Word History

Etymology

deoxyribonucleic acid

First Known Use

1944, in the meaning defined above

Time Traveler
The first known use of DNA was in 1944

Browse Nearby Words

Cite this Entry

“DNA.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/DNA. Accessed 7 Apr. 2026.

Kids Definition

: any of various nucleic acids that are located especially in cell nuclei, are usually the chemical basis of heredity, and are composed of two nucleotide chains held together by hydrogen bonds in a pattern resembling a flexible twisted ladder compare rna

Medical Definition

: any of various nucleic acids that are usually the molecular basis of heredity, are constructed of a double helix held together by hydrogen bonds between purine and pyrimidine bases which project inward from two chains containing alternate links of deoxyribose and phosphate, and that in eukaryotes are localized chiefly in cell nuclei

called also deoxyribonucleic acid

see recombinant dna

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