: any of various nucleic acids that are usually the molecular basis of heredity, are constructed of a double helix held together by hydrogen bonds between purine and pyrimidine bases (see base entry 1 sense 6b) which project inward from two chains containing alternate links of deoxyribose and phosphate, and that in eukaryotes are localized chiefly in cell nuclei compare recombinant dna

Illustration of DNA

Illustration of dna
  • A molecular model
  • 1 hydrogen
  • 2 oxygen
  • 3 carbon in the helical phosphate ester chains
  • 4 carbon and nitrogen in the cross-linked purine and pyrimidine bases
  • 5 phosphorus
  • B double helix

Examples of DNA in a Sentence

Recent Examples on the Web
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Menswear has long been part of the house’s DNA. Laure Guilbault, Vogue, 25 June 2026 Scientists have sequenced the genomes of our closest hominin relatives, Neanderthals and Denisovans, but the Homo naledi remains at Rising Star are older, and South Africa’s heat breaks down DNA faster and more thoroughly than where those other remains were found. ArsTechnica, 25 June 2026 Base editing, the process used to make the changes, only nicks one strand of DNA, avoiding the major DNA errors that made CRISPR unsafe. Carolyn Y. Johnson, Washington Post, 25 June 2026 Centellian24 comes from a Korean pharmaceutical company that spent decades researching Centella asiatica, so skin recovery is part of the brand’s DNA. Christa Joanna Lee, Allure, 24 June 2026 See All Example Sentences for DNA

Word History

Etymology

deoxyribonucleic acid

First Known Use

1944, in the meaning defined above

Time Traveler
The first known use of DNA was in 1944

Browse Nearby Words

Cite this Entry

“DNA.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/DNA. Accessed 27 Jun. 2026.

Kids Definition

: any of various nucleic acids that are located especially in cell nuclei, are usually the chemical basis of heredity, and are composed of two nucleotide chains held together by hydrogen bonds in a pattern resembling a flexible twisted ladder compare rna

Medical Definition

: any of various nucleic acids that are usually the molecular basis of heredity, are constructed of a double helix held together by hydrogen bonds between purine and pyrimidine bases which project inward from two chains containing alternate links of deoxyribose and phosphate, and that in eukaryotes are localized chiefly in cell nuclei

called also deoxyribonucleic acid

see recombinant dna

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