nucleotide

noun
nu·cle·o·tide | \ˈnü-klē-ə-ˌtīd, ˈnyü-\

Definition of nucleotide 

: any of several compounds that consist of a ribose or deoxyribose sugar joined to a purine or pyrimidine base and to a phosphate group and that are the basic structural units of nucleic acids (such as RNA and DNA) — compare nucleoside

Examples of nucleotide in a Sentence

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These are areas where sequences of nucleotides—the A, C, G and T letters that make up DNA—are repeated potentially tens of times, varying in length from family to family, Torkamani says. Karen Weintraub, Scientific American, "Genetic Testing to Reunite Immigrant Families Raises Issues of Privacy and Consent," 26 June 2018 The genetic differences picked out are often things called single-nucleotide polymorphisms (SNPs), which are places in the genome where a lone pair of bases, the chemical letters in which genetic messages are written, can vary between individuals. The Economist, "A big collaboration is trying to understand diseases of the psyche," 28 June 2018 Most new nucleotides attach to the growing oligo in 10 to 20 seconds, Palluk, Arlow, Keasling, and their colleagues report today in Nature Biotechnology. Robert F. Service, Science | AAAS, "New technique could help scientists create a gene in just 1 day," 18 June 2018 Normally a three-part string of nucleotides (usually represented by letters) codes for a particular type of protein. Keridwen Cornelius, Scientific American, "A Shot against Cancer Slated for Testing in Massive Dog Study," 7 June 2018 So the researchers decided to hack that hunger for nucleotides. Megan Molteni, WIRED, "A New Startup Wants to Use Crispr to Diagnose Disease," 26 Apr. 2018 In a frameshift an added or deleted molecular building block called a nucleotide throws a wrench into a cell’s replication gearbox. Keridwen Cornelius, Scientific American, "A Shot against Cancer Slated for Testing in Massive Dog Study," 7 June 2018 The tags are engineered to embed up to 250 bits of identifying information in the sequence of DNA nucleotides. Matt Allyn, Popular Mechanics, "How the Feds Will Use DNA To Track Legal Weed," 15 May 2018 For genomes, that means synthesizing DNA one nucleotide at a time and stringing together thousands of them. Sharon Begley, STAT, "Genome ‘writers’ set their first goal: recoding human cells to resist viruses," 1 May 2018

These example sentences are selected automatically from various online news sources to reflect current usage of the word 'nucleotide.' Views expressed in the examples do not represent the opinion of Merriam-Webster or its editors. Send us feedback.

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First Known Use of nucleotide

1908, in the meaning defined above

History and Etymology for nucleotide

International Scientific Vocabulary, irregular from nucle- + -ide

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Time Traveler for nucleotide

The first known use of nucleotide was in 1908

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More Definitions for nucleotide

nucleotide

noun
nu·cle·o·tide | \ˈn(y)ü-klē-ə-ˌtīd \

Medical Definition of nucleotide 

: any of several compounds that consist of a ribose or deoxyribose sugar joined to a purine or pyrimidine base and to a phosphate group and that are the basic structural units of RNA and DNA — compare nucleoside

More from Merriam-Webster on nucleotide

Britannica.com: Encyclopedia article about nucleotide

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