gene conversion

noun

Definition of gene conversion

: a genetic process that involves nonreciprocal meiotic recombination in heterozygotes in which a mismatched DNA sequence from one heteroduplex DNA strand is replaced with a sequence complementary to the other strand resulting in aberrant gametic ratios (such as 3:1) and that is observed especially in ascomycetous fungi

Examples of gene conversion in a Sentence

Recent Examples on the Web Their new experiments suggest that embryos borrow DNA templates from themselves to make repairs—a process called gene conversion—up to 40 percent of the time. Megan Molteni, Wired, "In Embryos, Crispr Can Cut Out Whole Chromosomes—That's Bad," 29 Oct. 2020

These example sentences are selected automatically from various online news sources to reflect current usage of the word 'gene conversion.' Views expressed in the examples do not represent the opinion of Merriam-Webster or its editors. Send us feedback.

First Known Use of gene conversion

1955, in the meaning defined above

Keep scrolling for more

Learn More about gene conversion

Time Traveler for gene conversion

Time Traveler

The first known use of gene conversion was in 1955

See more words from the same year

Statistics for gene conversion

Cite this Entry

“Gene conversion.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/gene%20conversion. Accessed 18 Jan. 2021.

Keep scrolling for more

More Definitions for gene conversion

gene conversion

noun

Medical Definition of gene conversion

: a genetic process that is sometimes associated with meiotic recombination in heterozygotes if heteroduplex DNA is formed, that involves the selective enzymatic excision of a mismatched DNA sequence from one heteroduplex strand and replacement with a nucleotide sequence complementary to the other strand so that the two DNA strands are genetically identical, and that results in aberrant gametic ratios (as 3:1 or 1:3 instead of 2:2)

More from Merriam-Webster on gene conversion

Britannica.com: Encyclopedia article about gene conversion

Comments on gene conversion

What made you want to look up gene conversion? Please tell us where you read or heard it (including the quote, if possible).

WORD OF THE DAY

Test Your Vocabulary

Words of Snow and Ice Quiz

  • image1037863653
  • Which of the following refers to thin, bending ice, or to the act of running over such ice?
True or False

Test your knowledge - and maybe learn something along the way.

TAKE THE QUIZ
Typeshift

Anagram puzzles meet word search.

TAKE THE QUIZ
Love words? Need even more definitions?

Subscribe to America's largest dictionary and get thousands more definitions and advanced search—ad free!