gene

noun

plural genes
: a specific sequence of nucleotides in DNA or RNA that is located usually on a chromosome and that is the functional unit of inheritance controlling the transmission and expression of one or more traits by specifying the structure of a particular polypeptide and especially a protein or controlling the function of other genetic material

Examples of gene in a Sentence

She inherited a good set of genes from her parents.
Recent Examples on the Web
Examples are automatically compiled from online sources to show current usage. Read More Opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback.
Differences in specific genes may cause a person to metabolize caffeine quickly or slowly. Brittany Lubeck, Verywell Health, 22 Oct. 2025 The researchers used long-term in vivo lineage tracing and gene expression profiling in mice to analyze how McSCs react to different kinds of DNA damage. Lucy Notarantonio, MSNBC Newsweek, 21 Oct. 2025 Starting fresh, scientists will be able to illuminate the mysteries of metabolism, development, and perhaps even consciousness in ways that editing genes cannot support. Big Think, 20 Oct. 2025 This catchall term often means genetic engineering – introducing new genes to an organism. Berly McCoy, NPR, 20 Oct. 2025 See All Example Sentences for gene

Word History

Etymology

German Gen, short for Pangen, from pan- + -gen

First Known Use

1909, in the meaning defined above

Time Traveler
The first known use of gene was in 1909

Cite this Entry

“Gene.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/gene. Accessed 23 Oct. 2025.

Kids Definition

gene

noun
: a part of DNA or sometimes RNA that is usually located on a chromosome and that contains chemical information needed to make a particular protein (as an enzyme) controlling or influencing an inherited bodily trait or activity (as eye color or metabolism) or that influences or controls the activity of another gene or genes

Medical Definition

gene

noun
: a specific sequence of nucleotides in DNA or RNA that is located usually on a chromosome and that is the functional unit of inheritance controlling the transmission and expression of one or more traits by specifying the structure of a particular polypeptide and especially a protein or controlling the function of other genetic material

called also determinant, determiner, factor

More from Merriam-Webster on gene

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