gene

noun

plural genes
: a specific sequence of nucleotides in DNA or RNA that is located usually on a chromosome and that is the functional unit of inheritance controlling the transmission and expression of one or more traits by specifying the structure of a particular polypeptide and especially a protein or controlling the function of other genetic material

Examples of gene in a Sentence

She inherited a good set of genes from her parents.
Recent Examples on the Web
Examples are automatically compiled from online sources to show current usage. Read More Opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback.
Decoding the body’s folds The team used advanced EpiSwitch® 3D Genomics technology from Oxford BioDynamics to study how DNA folds within cells, a process that affects which genes turn on or off. Neetika Walter, Interesting Engineering, 9 Oct. 2025 The disease, which typically emerges between 30 and 50 years of age, is caused by a mutation in the HTT gene, which triggers the cells to create a protein called huntingtin that can cause damage to the brain. Melissa Rudy, FOXNews.com, 8 Oct. 2025 Laia Foundation, which is currently raising money for gene replacement research for those with KARS. Angela Andaloro, PEOPLE, 7 Oct. 2025 Our findings support the idea that, rather than focusing on single genes, taking the whole genome into account would provide insight into how researchers understand what makes someone genetically predisposed to certain diseases and how those diseases develop. Santhosh Girirajan, The Conversation, 7 Oct. 2025 See All Example Sentences for gene

Word History

Etymology

German Gen, short for Pangen, from pan- + -gen

First Known Use

1909, in the meaning defined above

Time Traveler
The first known use of gene was in 1909

Cite this Entry

“Gene.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/gene. Accessed 10 Oct. 2025.

Kids Definition

gene

noun
: a part of DNA or sometimes RNA that is usually located on a chromosome and that contains chemical information needed to make a particular protein (as an enzyme) controlling or influencing an inherited bodily trait or activity (as eye color or metabolism) or that influences or controls the activity of another gene or genes

Medical Definition

gene

noun
: a specific sequence of nucleotides in DNA or RNA that is located usually on a chromosome and that is the functional unit of inheritance controlling the transmission and expression of one or more traits by specifying the structure of a particular polypeptide and especially a protein or controlling the function of other genetic material

called also determinant, determiner, factor

More from Merriam-Webster on gene

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