gene

noun

ˈjēn 

plural genes

: a specific sequence of nucleotides in DNA or RNA that is located usually on a chromosome and that is the functional unit of inheritance controlling the transmission and expression of one or more traits by specifying the structure of a particular polypeptide and especially a protein or controlling the function of other genetic material

Examples of gene in a Sentence

She inherited a good set of genes from her parents.

Recent Examples on the Web

Causing a secondary cancer may be an acceptable risk when treating a life-threatening cancer, but probably not for autoimmunity, says Matt Lunning, medical director for gene and cellular therapy at Nebraska Medicine in Omaha. —Amber Dance, ArsTechnica, 17 May 2026

Clark simply has the clutch gene. —Matt Reigle Outkick, FOXNews.com, 16 May 2026

Epigenetics explains how your behaviors and environment can affect how your genes act. —Julie Scott, Verywell Health, 15 May 2026

Honing in on the gene itself allows the drug to target the mechanism behind the cancer while potentially limiting the side effects that come with broader treatments. —Mary Walrath-Holdridge, USA Today, 14 May 2026

Word History

Etymology

German Gen, short for Pangen, from pan- + -gen

First Known Use

1909, in the meaning defined above

Phrases Containing gene

• gene conversion
• gene editing
• gene flow
• gene frequency
• gene mutation
• gene pool
• gene-splicing
• gene therapy
• lethal gene
• regulator gene
• regulatory gene
• structural gene
• tumor suppressor gene

Rhymes for gene

• bean
• bein
• bien
• bouin
• clean
• deen
• acetylcysteine
• antisubmarine
• dichlorobenzene
• dimethylamine
• diphenylamine
• ethanolamine

Kids Definition

gene

noun

ˈjēn 

: a part of DNA or sometimes RNA that is usually located on a chromosome and that contains chemical information needed to make a particular protein (as an enzyme) controlling or influencing an inherited bodily trait or activity (as eye color or metabolism) or that influences or controls the activity of another gene or genes

Medical Definition

gene

noun

ˈjēn 

: a specific sequence of nucleotides in DNA or RNA that is located usually on a chromosome and that is the functional unit of inheritance controlling the transmission and expression of one or more traits by specifying the structure of a particular polypeptide and especially a protein or controlling the function of other genetic material

called also determinant, determiner, factor