gene

noun

plural genes
: a specific sequence of nucleotides in DNA or RNA that is located usually on a chromosome and that is the functional unit of inheritance controlling the transmission and expression of one or more traits by specifying the structure of a particular polypeptide and especially a protein or controlling the function of other genetic material

Examples of gene in a Sentence

She inherited a good set of genes from her parents.
Recent Examples on the Web
Examples are automatically compiled from online sources to show current usage. Read More Opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback.
Exciting but scary findings During another of the key microplastics studies published so far, researchers at the University of Rhode Island tested mice that had been modified to include a gene, APOE4, linked to Alzheimer’s disease. Michael Hawthorne, Chicago Tribune, 21 June 2026 The most striking similarity was in a gene called FBXW7, a critical tumor suppressor for people and cats. Kyle Melnick The Washington Post, Arkansas Online, 21 June 2026 The deeper and much harder question is how those genes are used, or regulated, a question that seems to involve some and perhaps much of the rest of the genome. Philip Ball, Quanta Magazine, 18 June 2026 The paper treads similar ground as previous research, which has noted large language models’ ability to search genomes for genes that have been sequenced after a patient was first seen in a hospital. Jared Perlo, NBC news, 18 June 2026 See All Example Sentences for gene

Word History

Etymology

German Gen, short for Pangen, from pan- + -gen

First Known Use

1909, in the meaning defined above

Time Traveler
The first known use of gene was in 1909

Cite this Entry

“Gene.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/gene. Accessed 23 Jun. 2026.

Kids Definition

gene

noun
: a part of DNA or sometimes RNA that is usually located on a chromosome and that contains chemical information needed to make a particular protein (as an enzyme) controlling or influencing an inherited bodily trait or activity (as eye color or metabolism) or that influences or controls the activity of another gene or genes

Medical Definition

gene

noun
: a specific sequence of nucleotides in DNA or RNA that is located usually on a chromosome and that is the functional unit of inheritance controlling the transmission and expression of one or more traits by specifying the structure of a particular polypeptide and especially a protein or controlling the function of other genetic material

called also determinant, determiner, factor

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