Definition of estrange
1 : to arouse especially mutual enmity or indifference in (someone) where there had formerly been love, affection, or friendliness : alienate John's excesses gradually estranged him from his mother …— Philip Norman She became estranged from her family.
2 : to remove from customary environment or associations The first words spoken were not those of one becoming estranged from this world, and already permitted to stray at times into realms foreign to the living.— Charlotte Brontë
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