Synonyms of malignancy

malignancy

noun

mə-ˈlig-nən(t)-sē 

as in malice

the desire to cause pain for the satisfaction of doing harm

her irrepressible malignancy was such that she even attacked her friends behind their backs

Synonyms & Similar Words

• malice
• venom
• hatred
• cruelty
• spite
• malignity
• hostility
• malevolence
• hatefulness
• maliciousness
• malignance
• meanness
• spleen
• jealousy
• spitefulness
• contempt
• viciousness
• bitterness
• disgust
• despite
• nastiness
• hate
• disdain
• jaundice
• cattiness
• resentment
• antagonism
• enmity
• animosity
• abhorrence
• abusiveness
• loathing
• antipathy
• abomination
• rancor
• distaste
• horror
• vindictiveness
• grudge
• repugnance
• ill will
• repulsion
• revulsion
• virulence
• execration
• bile
• invidiousness
• vengefulness
• scorn
• aversion
• despicableness
• mean-spiritedness
• pique
• bitchiness
• vitriol
• bitchery

Antonyms & Near Antonyms

• devotion
• love
• passion
• hospitality
• friendliness
• worship
• amity
• amiability
• cordiality
• civility
• infatuation
• understanding
• adoration
• affection
• ardor
• veneration
• kindness
• charity
• friendship
• sympathy
• kindliness
• amicability
• empathy
• goodwill
• comity

Example Sentences

Recent Examples of malignancy

Cancers of the head and neck include malignancies affecting the mouth and throat (called the oral cavity and pharynx), the voice box (larynx), the sinuses and nasal cavities, and the salivary glands. — Mikkael Sekeres, Washington Post, 18 May 2026

And in 2025, UCSD researchers were awarded $25 million to develop biomarkers capable of anticipating tumor evolution and predicting how malignancies will respond to treatment. — Paul Sisson, San Diego Union-Tribune, 13 Apr. 2026

An effective treatment for pancreatic cancer would represent a major advance against one of the most lethal malignancies. — IEEE Spectrum, 22 Dec. 2025

The researchers will now investigate its efficacy in breast cancer, pancreatic cancer, melanoma and other malignancies, and fine tune delivery and dosage methods. — New Atlas, 16 Dec. 2025