mutation

play
noun mu·ta·tion \ myü-ˈtā-shən \

Definition of mutation

1 :a significant and basic alteration :change
2 :umlaut
3 a :a relatively permanent change in hereditary material that involves either a change in chromosome structure or number (as in translocation, deletion, duplication, or polyploidy) or a change in the nucleotide sequence of a gene's codons (as in frameshift or missense errors) and that occurs either in germ cells or in somatic cells but with only those in germ cells being capable of perpetuation by sexual reproduction
  • Mutations known to cause disease have been identified in approximately 1000 genes.
  • —Alan E. Guttmacher and Francis S. Collins
; also :the process of producing a mutation
  • Microorganisms have been used extensively to study mutation
  • —George A. Wistreich et al.
b :an individual, strain, or trait resulting from mutation
  • The worst E. coli bacterium, E. coli 0157:H, a mutation discovered in 1982 that has at least sixty-two subtypes, causes hemorrhagic colitis …
  • —Wayne Biddle

mutational

play \-shnəl, -shə-nᵊl\ adjective

mutationally

adverb

Examples of mutation in a Sentence

  1. The cat's short tail is the result of mutation.

  2. The condition is caused by a genetic mutation.

  3. The cat's short tail is the result of a mutation.

  4. The building is a mutation of the original design.

Recent Examples of mutation from the Web

These example sentences are selected automatically from various online news sources to reflect current usage of the word 'mutation.' Views expressed in the examples do not represent the opinion of Merriam-Webster or its editors. Send us feedback.

First Known Use of mutation

14th century

Other Genetics Terms


MUTATION Defined for Kids

mutation

play
noun mu·ta·tion \ myü-ˈtā-shən \

Definition of mutation for Students

:a change in a gene or the resulting new trait it produces in an individual

Medical Dictionary

mutation

play
noun mu·ta·tion \ myü-ˈtā-shən \

medical Definition of mutation

1 :a relatively permanent change in hereditary material that involves either a change in chromosome structure or number (as in translocation, deletion, duplication, or polyploidy) or a change in the nucleotide sequence of a gene's codons (as in frameshift or missense errors) and occurs either in germ cells or in somatic cells but with only those in germ cells being capable of perpetuation by sexual reproduction; also :the process of producing a mutation
2 :an individual, strain, or trait resulting from mutation

mutational

play \-shnəl, -shən-ᵊl\ adjective

mutationally

play \\ adverb


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