missense

adjective
mis·​sense | \ ˈmis-ˌsen(t)s How to pronounce missense (audio) \

Definition of missense

: relating to or being a gene mutation involving alteration of one or more codons so that different amino acids are determined — compare antisense, nonsense

Examples of missense in a Sentence

Recent Examples on the Web

A missense mutation, for example, swaps one amino acid in the protein for another. Nicholette Zeliadt, Washington Post, "Is there such a thing as an autism gene?," 30 June 2017

These example sentences are selected automatically from various online news sources to reflect current usage of the word 'missense.' Views expressed in the examples do not represent the opinion of Merriam-Webster or its editors. Send us feedback.

First Known Use of missense

1961, in the meaning defined above

History and Etymology for missense

mis- + -sense (as in nonsense)

Keep scrolling for more

Learn More about missense

Dictionary Entries near missense

misseem

missel thrush

missend

missense

mis-set

misset

missey-moosey

Statistics for missense

Last Updated

23 Apr 2019

Look-up Popularity

Time Traveler for missense

The first known use of missense was in 1961

See more words from the same year

Keep scrolling for more

More Definitions for missense

missense

adjective
mis·​sense | \ ˈmis-ˌsen(t)s How to pronounce missense (audio) \

Medical Definition of missense

 (Entry 1 of 2)

: relating to or being a gene mutation involving alteration of one or more codons so that different amino acids are determined missense mutations a missense suppressor — compare antisense, nonsense

missense

noun

Medical Definition of missense (Entry 2 of 2)

: missense genetic mutation — compare nonsense

More from Merriam-Webster on missense

Rhyming Dictionary: Words that rhyme with missense

Comments on missense

What made you want to look up missense? Please tell us where you read or heard it (including the quote, if possible).

WORD OF THE DAY

behavior toward others

Get Word of the Day daily email!

Test Your Vocabulary

Words for Summer: A Quiz

  • a closeup of a sunflower
  • Which of the following words means “of or relating to summer”?
True or False

Test your knowledge - and maybe learn something along the way.

TAKE THE QUIZ
Word Winder's CrossWinder

Test Your Knowledge - and learn some interesting things along the way.

TAKE THE QUIZ
Love words? Need even more definitions?

Subscribe to America's largest dictionary and get thousands more definitions and advanced search—ad free!