genetic mutation

noun
plural genetic mutations

Definition of genetic mutation

: a permanent alteration in the nucleotide sequence of one or more genes or in the number or structure of one or more chromosomes Lacking working copies of the p53 gene, cells can begin to divide without check, though several other genetic mutations are thought to be needed to foster a full-blown malignancy.— Natalie Angier

First Known Use of genetic mutation

1915, in the meaning defined above

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The first known use of genetic mutation was in 1915

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genetic mutation

noun

Medical Definition of genetic mutation

: a permanent alteration in the nucleotide sequence of one or more genes or in the number or structure of one or more chromosomes Gaucher's disease results from one of many genetic mutations that can either slow or prevent the breakdown of certain glycolipids, which accumulate in storage vesicles and eventually kill cells.— Joseph Alper

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