genetic modification

noun

: the modification of an organism's genetic material that involves using applied techniques of genetics and biotechnology to alter or delete a DNA segment or to insert a new DNA segment from a different species in order to express (see express entry 1 sense 4) or suppress (see suppress sense 6) a targeted trait or traits : genetic engineering

… in a breakthrough in genetic modification—a technique that scientists have already used … in the development of hardier hybrids of corn, cotton, canola, and soybeans—plant geneticists and computer scientists had begun to isolate the groups of genes that control such factors as elongation … in certain types of fruits and vegetables.

—Frederick Kaufman

… the main effect of genetic modification will be to reduce dependence on chemical sprays by improving resistance to diseases and pests …

—Matt Ridley

compare genetically modified, genetically modified organism

Examples of genetic modification in a Sentence

Recent Examples on the Web

Irradiation and genetic modification are two other methods of sterile treatment. — Alula Alderson, Sacbee.com, 8 July 2026

Some countries are launching trials of gene drives to control malaria, which involve forcing a genetic modification into a mosquito population to reduce their numbers or their tolerance for Plasmodium. — Jacob A Tennessen, The Conversation, 26 Mar. 2026

Because optogenetic implants require genetic modification of neurons to work, they are not yet approved for human use. — New Atlas, 29 Dec. 2025

Conservationists are also discussing the use of genetic modification to control animal populations, using what's known as a gene drive. — Lauren Sommer, NPR, 18 Sep. 2025

Word History

First Known Use

1923, in the meaning defined above

Rhymes for genetic modification

• deindustrialization
• immunoprecipitation
• individualisation
• individualization
• institutionalisation
• institutionalization
• internationalization
• neovascularization
• operationalization
• abbreviation
• abomination
• acceleration

Medical Definition

genetic modification

noun

: the modification of an organism's genetic material that involves using applied techniques of genetics and biotechnology to alter or delete a DNA segment or to insert a new DNA segment from a different species in order to express (see express sense 3) or suppress (see suppress sense 3) a targeted trait or traits : genetic engineering

Erectile dysfunction is another complication of diabetes that can manifest due to vasculopathy and neuropathy that could also be treated with genetic modification.

—Cleyton C. Domingues et al., Genetic Engineering: An Insight into the Strategies and Applications

see genetically modified, genetically modified organism